Annals of Intensive Care

Table 3 (A) Accuracy of age and SAPS II to detect ARC. (B) Accuracy of SCr, Cockcroft and Gault, Robert, sMDRD, and CKD-EPI formulas to detect ARC

From: Screening of patients with augmented renal clearance in ICU: taking into account the CKD-EPI equation, the age, and the cause of admission

(A)	AUC	IC 95 % AUC	Cut-off	Gray zone	Sensitivity	Specificity	PPV	NPV
Age (years)	0.74	0.69–0.79	≤58	25-60	89.2	52	48	90.5
SAPS II	0.59	0.54–0.64	<54	24-62	76	38	37	76

(B) Formula eGFR	AUC	IC 95 % AUC	Cut-Off	Gray zone	Sensitivity	Specificity	PPV	NPV
SCr	0.66	0.61–0.71	≤71	45.75–88.5	73.33	53.33	44	80
CG	0.79	0.74–0.83	>107.50	95.5–148.6	83.33	62.92	53	88
CKD-EPI	0.79	0.75–0.83	>108.11	90–122.8	75.00	74.58	60	86
Robert	0.75	0.70–0.79	>83.19	63.3–104.7	67.50	70.83	54	81
sMDRD	0.73	0.68–0.78	>107.63	88–150.3	76.67	61.67	50	84

AUC area under the curve, Gray zone based on Cannesson method, PPV positive predictive value (%), NPV negative predictive value (%), for SCr cut-off and gray zone are expressed in µmol/l, for eGFRs cut-off and gray zone are expressed in ml/min/1.73 m²

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