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Table 2 Primary and secondary outcomes

From: Tolvaptan for hyponatremia with preserved sodium pool in critically ill patients

Primary outcome

 ≥4 mmol/l increase in serum sodium over baseline at 24 h—n (%)

31/38 (81.6 %)

Secondary outcomes

 Absolute increase in serum sodium over baseline at 24 h—mmol/l

6.7 ± 3.4

 Absolute increase in serum sodium over baseline at 72 h—mmol/l

5.5 ± 3.7

 Absolute reduction in urine sodium over baseline at 24 h—mmol/l

-68.0 ± 39.9

 ≥12 mmol/l increase in serum sodium over baseline at 24 h—n (%)

4/38 (10.5 %)

 Average hourly increase in serum sodium—mmol/l*h

0.28 ± 0.14