From: Tolvaptan for hyponatremia with preserved sodium pool in critically ill patients
Primary outcome | |
 ≥4 mmol/l increase in serum sodium over baseline at 24 h—n (%) | 31/38 (81.6 %) |
Secondary outcomes | |
 Absolute increase in serum sodium over baseline at 24 h—mmol/l | 6.7 ± 3.4 |
 Absolute increase in serum sodium over baseline at 72 h—mmol/l | 5.5 ± 3.7 |
 Absolute reduction in urine sodium over baseline at 24 h—mmol/l | -68.0 ± 39.9 |
 ≥12 mmol/l increase in serum sodium over baseline at 24 h—n (%) | 4/38 (10.5 %) |
 Average hourly increase in serum sodium—mmol/l*h | 0.28 ± 0.14 |