Table 3 Comparison of demographic and clinical variables between vitamin D deficient and ‘not deficient’ groups
Outcome variables | Vitamin D deficiency N = 75 | ‘No deficiency’ N = 26 | P value |
|---|---|---|---|
Age (yrs) | 4 (0.5–9) | 1 (0.4–8) | 0.12 |
Female gender | 39 (53) | 10 (37) | 0.16 |
Weight for age | |||
Moderate under-nutrition | 31 (80) | 8 (31) | 0.33* |
Severe under-nutrition | 21 (70) | 9 (34) | 0.66* |
PIM2-probability of death (%) (median, IQR) | 12.5 (8.6–23.5) | 11.5 (6.8–30) | 0.45 |
PELOD score (median, IQR) | 21 (11–22) | 21 (10–21) | 0.09 |
Diagnosis (infections) | 47 (64) | 16 (59) | 0.69 |
Hypocalcemia | |||
Total | 27 (36) | 6 (37.5) | 0.9 |
Ionized | 58 (77) | 15 (94) | 0.14 |
Serum calcium (median, IQR) | |||
Total (mg/dL) | 8.5 (7.4–8.9) | 8.7 (7.1–9.2) | 0.30 |
Ionized (mmol/L) | 0.65 (0.4–0.8) | 0.70 (0.63–0.9) | 0.21 |
Parathyroid levels (pg/mL) | 16 (1.4) | 16.6 (5) | 0.36 |
Need for fluid boluses in first 6 h | 44 (59) | 12 (38) | 0.14 |
Need for mechanical ventilation (n %) | 43 (57) | 10 (39) | 0.10 |
Duration of ventilation (days) | |||
Median (IQR) | 6.5 (3.5–14) | 7 (2–13) | 0.55 |
Need for inotropes (n %) | 40 (53) | 8 (31) | 0.06 |
Inotrope score | 1320 (960–7040) | 2440 (1440–3120) | 0.23 |
Duration of inotrope therapy, days (median, IQR) | 2 (2–4) | 1.5 (1–2) | 0.15 |
Duration of PICU stay | 7 (2–12) | 3 (2–5) | 0.006 |
Mortality (n %) | 23 (31) | 8 (31) | 1.0 |