Table 4 Clinical evolution as a function of the final diagnosis of invasive candidiasis
From: Systemic antifungal therapy for proven or suspected invasive candidiasis: the AmarCAND 2 study
Final diagnosis | ||||
|---|---|---|---|---|
Candidaemia n = 160 | CIAI n = 193 | Deep-seated candidiasis n = 74 | Non-confirmed IC n = 432 | |
SOFA score at D0 | ||||
Mean ± SD | 7.7 ± 4.8 | 7.2 ± 4.5 | 7.7 ± 4.5 | 8.4 ± 4.3 |
Median (min; max) | 7 (0; 23) | 7 (0; 19) | 7.5 (0; 17) | 8 (0; 24) |
SOFA score at D7 | ||||
Mean ± SD | 6.9 ± 6.0 | 4.9 ± 5.1 | 6.5 ± 5.8 | 6.8 ± 5.3 |
Median (min; max) | 5 (0; 24) | 3 (0; 24) | 5 (0; 21) | 6 (0; 24) |
Clinical outcome n (%) | ||||
Cured | 89 (55.6) | 135 (70.0) | 48 (64.9) | 261 (60.4) |
Failure | 27 (16.85) | 20 (10.35) | 12 (16.2) | 42 (9.7) |
Not determined | 33 (20.6) | 27 (14.0) | 13 (17.6) | 89 (20.6) |
Information not available | 11 (6.9) | 11 (5.7) | 1 (1.3) | 40 (9.3) |
Status on D28, n (%) | ||||
Alive | 90 (56.3) | 135 (70.0) | 53 (71.6) | 271 (62.7) |
Dead | 64 (40.0) | 49 (25.4) | 19 (26.7) | 138 (32.0) |
Lost to follow-up after ICU discharge | 6 (3.7) | 9 (4.6) | 2 (2.7) | 23 (5.3) |
Length of SAT among those alive (days) | ||||
Mean ± SD | 24 ± 16 | 20 ± 14 | 28 ± 25 | 12 ± 10 |
Median | 20 | 17 | 21 | 10 |