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Table 4 Clinical evolution as a function of the final diagnosis of invasive candidiasis

From: Systemic antifungal therapy for proven or suspected invasive candidiasis: the AmarCAND 2 study

  Final diagnosis
  Candidaemia
n = 160
CIAI
n = 193
Deep-seated candidiasis
n = 74
Non-confirmed IC
n = 432
SOFA score at D0
 Mean ± SD 7.7 ± 4.8 7.2 ± 4.5 7.7 ± 4.5 8.4 ± 4.3
 Median (min; max) 7 (0; 23) 7 (0; 19) 7.5 (0; 17) 8 (0; 24)
SOFA score at D7
 Mean ± SD 6.9 ± 6.0 4.9 ± 5.1 6.5 ± 5.8 6.8 ± 5.3
 Median (min; max) 5 (0; 24) 3 (0; 24) 5 (0; 21) 6 (0; 24)
Clinical outcome n (%)     
 Cured 89 (55.6) 135 (70.0) 48 (64.9) 261 (60.4)
 Failure 27 (16.85) 20 (10.35) 12 (16.2) 42 (9.7)
 Not determined 33 (20.6) 27 (14.0) 13 (17.6) 89 (20.6)
 Information not available 11 (6.9) 11 (5.7) 1 (1.3) 40 (9.3)
Status on D28, n (%)     
 Alive 90 (56.3) 135 (70.0) 53 (71.6) 271 (62.7)
 Dead 64 (40.0) 49 (25.4) 19 (26.7) 138 (32.0)
Lost to follow-up after ICU discharge 6 (3.7) 9 (4.6) 2 (2.7) 23 (5.3)
Length of SAT among those alive (days)    
 Mean ± SD 24 ± 16 20 ± 14 28 ± 25 12 ± 10
 Median 20 17 21 10
  1. cIAI complicated intra-abdominal infections, IC invasive candidiasis, SAT systemic antifungal therapy, SD standard deviation