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Annals of Intensive Care

Table 3 Values for prediction of AKI within 72 h

From: Plasma endostatin may improve acute kidney injury risk prediction in critically ill patients

Statistic Estimate (95 % CI) P valuea
AUC endostatin alone 0.726 (0.603 to 0.848) <0.001
AUC cystatin C alone 0.674 (0.535 to 0.812) 0.01
AUC NGAL alone 0.577 (0.430 to 0.723) 0.22
AUC early oliguria 0.618 (0.509 to 0.727) 0.04
AUC clinical model 0.759 (0.646 to 0.872) <0.001
AUC clinical model + endostatin 0.839 (0.752 to 0.925) <0.001
AUC clinical model + cystatin C 0.776 (0.662 to 0.890) <0.001
AUC clinical model + NGAL 0.766 (0.657 to 0.874) <0.001
NRI (endostatin) 0.268 (0.010 to 0.526) 0.04
IDI (endostatin) 0.073 (0.038 to 0.142) 0.04
NRI (cystatin C) 0.06 (−0.16 to 0.28) 0.63
IDI (cystatin C) 0.012 (−0.013 to 0.037) 0.34
NRI (NGAL) 0.035 (−0.15 to 0.22) 0.71
IDI (NGAL) 0.0061 (−0.013 to 0.025) 0.53
  1. AUC area under the receiver operating characteristics curve, NRI net reclassification improvement, IDI integrated discrimination improvement
  2. a P values for AUC assess the difference from 0.5
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