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Table 3 Drugs involved in preventable and unpreventable adverse drug events according to the anatomical therapeutic and chemical (ATC) classification (one ADE can be due to more than one drug)

From: An observational study of adult admissions to a medical ICU due to adverse drug events

Drugs classification according to ATC classification system

Preventable ADE [n (%)]

Unpreventable ADE [n (%)]

All ADE

Antineoplastic and immunomodulating agents

3 (3 %)

41 (41 %)

44 (20 %)

Cardiovascular system

36 (30 %)

8 (8 %)

44 (20 %)

Blood and blood-forming organs

20 (17 %)

23 (23 %)

43 (20 %)

Nervous system

30 (25 %)

13 (13 %)

43 (20 %)

Systemic hormonal preparation (except sex hormones and insulin)

9 (8 %)

7 (7 %)

16 (7 %)

Anti-infective for systemic use

7 (6 %)

5 (5 %)

12 (5 %)

Alimentary tract and metabolism

4 (3 %)

2 (2 %)

6 (3 %)

Musculoskeletal system

6 (5 %)

0 (0 %)

6 (3 %)

Others

4 (3 %)

1 (1 %)

5 (2 %)

Total

119 (100 %)

100 (100 %)

219 (100 %)

  1. The distribution of ATC classes implied in preventable and unpreventable ADE was compared: P = 2.2 × 10−13