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Table 1 Baseline characteristics

From: Respiratory mechanics and lung stress/strain in children with acute respiratory distress syndrome

Characteristic ARDS patients (n = 10) Control patients (n = 10) p value
Age (years) 2.5 [1.0–5.5] 3.0 [1.7–7.2] 0.62
Male sex, no. of patients (%) 7 (70) 4 (40) 0.37
Height (cm) 99.5 ± 22.2 105.7 ± 14.7 0.47
Weight (kg) 12.7 [10.0–20.2] 15.0 [14.7–18.0] 0.16
Body mass index (kg/m2) 15.1 ± 2.4 15.3 ± 3.0 0.88
V T (ml) 120.0 [98.7–182.5] 145.0 [127.5–162.5] 0.43
V T/IBW (ml/kg) 9.1 [7.8–10.0] 9.7 [8.5–10.2] 0.54
Days of ventilation before study 2 [1–4] 0 [0–1] 0.04
ARDS classification, no (%)    
 Mild 6 (60)   
 Moderate 2 (20)   
 Severe 2 (20)   
Respiratory rate (bpm) 27 ± 7 22 ± 5 0.09
Minute ventilation (l/min) 3.4 ± 1.1 3.2 ± 0.8 0.64
Airway plateau pressure (cmH2O) 24.2 ± 4.0 15.1 ± 3.1 <0.001
PEEP (cmH2O) 8.4 ± 2.3 3.5 ± 1.8 <0.001
PaO2/FiO2 ratio 206 ± 86 389 ± 73 <0.001
PaCo2 (mmHg) 44.0 [37.2–52.5] 40.5 [38.0–45.5] 0.40
FRC (ml) 162.2 ± 67.6 288.1 ± 107.3 0.006
FRC (ml/kg) 10.4 [9.1–14.3] 16.6 [11.7–24.6] 0.04
Admission diagnosis, no (%)    0.004
 Sepsis 2 (20) 0  
 Infection 4 (40) 0  
 ARDS ndd 3 (30) 0  
 Post-surgery 0 4 (40)  
 Neurological diseases 0 4 (40)  
 Other 1 (10) 2 (20)  
  1. Data presented as mean values (SD) or as median [IQ] or as number of subjects (%) as appropriate
  2. V T tidal volume, IBW ideal body weight, ARDS acute respiratory distress syndrome, PEEP positive end-expiratory pressure, PaO 2 /FiO 2 ratio of partial pressure of arterial oxygen and fraction of inspired oxygen, PaCO 2 partial pressure of arterial carbon dioxide, FRC functional residual capacity