From: Respiratory mechanics and lung stress/strain in children with acute respiratory distress syndrome
 | PEEP (cmH2O) | p value | |||||||
---|---|---|---|---|---|---|---|---|---|
4 | 12 | Pathology | PEEP | V T | |||||
V T | |||||||||
8 | 10 | 12 | 8 | 10 | 12 | ||||
Airway plateau pressure (cmH2O) | <0.001 | <0.001 | <0.001 | ||||||
 ARDS patients | 18.6 ± 3.6 | 21.7 ± 4.3 | 23.4 ± 3.3 | 26.5 ± 2.7 | 29.2 ± 2.7 | 31.9 ± 2.6 |  |  |  |
 Control patients | 13.3 ± 2.1 | 14.7 ± 2.7 | 16.0 ± 3.1 | 21.2 ± 2.3 | 22.7 ± 2.6 | 24.3 ± 3.3 |  |  |  |
Respiratory system compliance (ml/cmH2O) | <0.001 | 0.36 | 0.40 | ||||||
 ARDS patients | 9.6 ± 4.6 | 9.9 ± 5.6 | 10.2 ± 4.4 | 9.0 ± 4.0 | 9.4 ± 4.2 | 9.6 ± 4.2 |  |  |  |
 Control patients | 16.5 ± 3.4 | 17.9 ± 4.8 | 19.0 ± 6.9 | 16.0 ± 3.6 | 17.1 ± 4.3 | 17.6 ± 4.5 |  |  |  |
Lung compliance (ml/cmH2O) | <0.001 | 0.56 | 0.43 | ||||||
 ARDS patients | 11.5 ± 6.0 | 11.6 ± 5.5 | 12.0 ± 5.5 | 10.2 ± 4.5 | 10.9 ± 5.1 | 11.3 ± 4.9 |  |  |  |
 Control patients | 21.8 ± 4.6 | 23.8 ± 6.2 | 25.5 ± 8.0 | 22.4 ± 6.0 | 23.4 ± 8.3 | 24.2 ± 7.9 |  |  |  |
Chest wall compliance (ml/cmH2O) | 0.49 | 0.60 | 0.63 | ||||||
 ARDS patients | 76.3 ± 29.6 | 79.2 ± 35.0 | 74.5 ± 26.3 | 122.6 ± 113.0 | 81.4 ± 30.3 | 73.8 ± 52.1 |  |  |  |
 Control patients | 99.5 ± 99.1 | 85.6 ± 55.8 | 98.2 ± 69.1 | 85.5 ± 61.6 | 90.1 ± 55.9 | 94.4 ± 69.1 |  |  |  |
End-expiratory lung volume (ml) | <0.001 | <0.001 | 0.97 | ||||||
 ARDS patients | 211.0 ± 116.1 | 216.5 ± 115.2 | 216.7 ± 117.7 | 346.2 ± 177.6 | 361.2 ± 185.6 | 374.2 ± 183.9 |  |  |  |
 Control patients | 386.2 ± 156.6 | 384.7 ± 151.7 | 386.9 ± 156.4 | 619.2 ± 230.2 | 623.1 ± 219.9 | 622.1 ± 207.2 |  |  |  |