Table 3 Randomized controlled trials in adult ECMO
From: Concepts from paediatric extracorporeal membrane oxygenation for adult intensivists
Author (ref no) | CMV (lived/total) | ECMO (lived/total) | Pro-ECMO | Anti-ECMO | Today’s perspective |
|---|---|---|---|---|---|
Zapol et al. [1] | 4/48 (8 %) | 4/42 (10 %) | Change needed? Different patients with different diseases | Does not work | VV not used, ECMO duration arbitrarily limited to 5 days, ECMO started very late |
Morris et al. [7] | 8/19 (42 %) | 7/21 (33 %) | 2/3 death due to bleeding, learning curve | Does not work, protocols are better | Small study, outdated ECMO technology, training is important |
Peek et al. [8] | 41/87 (47 %) | 57/90 (63 %) | ECMO works | Only 68 % received ECMO | Intention to treat analysis, ECMO in care plan probably beneficial but still unproven |