Table 1 Baseline demographic and patients’ clinical characteristics

Age: age (mean + SD)

50 ± 16

53 ± 17

0.28

Sex ratio

2.31

1.81

0.49

SAPS II at inclusion

39 + 13

40 + 14

0.65

SOFA at inclusion

7.03 + 3.8

6.5 + 4.1

0.43

Reasons for admission [n (%)]

 Respiratory distress

32 (44 %)

29 (38 %)

 Neurological causes

23 (31.5 %)

26 (34 %)

 Metabolic disorders

11 (15 %)

15 (20 %)

 Intoxications

5 (7 %)

3 (4 %)

 Others

2 (2.5 %)

3 (4 %)

0.92

Length of stay before inclusion: days [mean + SD (median)]

11.28 ± 9 (9)

11.14 ± 8.8 (9)

0.49

Previous antibiotic use [n (%)]

49 (67 %)

46 (60 %)

1

Colistin in monotherapy [n (%)]

13 (17.8 %)

12 (15.7 %)

1

Co-administered antibiotics [n (%)]

60 (80.3 %)

64 (82 %)

0.62

 β-lactams

32

37

1

 Aminoglycosides

11

12

1

 Quinolones or macrolides

5

6

0.79

 Tygecyclin

8

8

0.58

 Glycopeptides

8

6

Iodinated contrast agent

14 (19 %)

17 (22.3 %)

0.68