Table 3 Significant demographic and clinical variables potentially associated with in-hospital mortality
Nonsurvivors (n = 114) | Survivors (n = 304) | P value | |
|---|---|---|---|
Age (mean years ± SD) | 74.69 ± 10.43 | 68.38 ± 13.58 | 0.006 |
Comorbidities [n (%)] | |||
Chronic renal failure | 21 (18.4) | 18 (5.9) | <0.001 |
Acute renal failure, dialysis | 3 (2.6) | 6 (2.0) | <0.001 |
Immunosuppression | 11 (9.6) | 4 (1.3) | <0.001 |
Postoperative status | 0.001 | ||
Severe sepsis | 12 (10.5) | 139 (45.7) | |
Septic shock | 100 (87.7) | 163 (53.6) | |
Biochemical parameters at ICU (mean ± SD) | |||
Sodium (mEq/L) | 137.64 ± 6.8 | 136.05 ± 4.81 | <0.001 |
Creatinine (mg/dL) | 2.18 ± 1.71 | 1.21 ± 0.77 | <0.001 |
Lactate (mmol/L) | 34.90 ± 26.16 | 24.13 ± 19.28 | 0.005 |
Procalcitonin (ng/mL) | 24.48 ± 36.42 | 16.27 ± 30.28 | 0.043 |
HCO3 − (mEq/L) | 20.42 ± 7.28 | 21.73 ± 5.52 | 0.030 |
Postoperative management | |||
Low-dose steroid therapy | 25 (21.9) | 97 (31.9) | <0.001 |
Blood transfusions, units | 4.43 ± 6.90 | 1.74 ± 4.16 | <0.001 |
Politransfusion (>10 units) [n (%)] | 26 (22.8) | 25 (8.2) | <0.001 |
Mechanical ventilation | |||
Total duration (days ± SD) | 7.38 ± 11.70 | 1.69 ± 4.48 | <0.001 |
Patients requiring >48 h [n (%)] | 50 (43.9) | 46 (15.1) | <0.001 |
Clinical outcome | |||
Stay at ICU, median days (IQR) | 8.0 (3.8–14.3) | 3.0 (1.0–6.0) | <0.001 |
Total stay at the hospital, median days (IQR) | 21.0 (9.3–43.8) | 21.0 (12.3–35.0) | 0.004 |
VAP | 18 (15.8) | 22 (7.2) | 0.008 |