Table 1 Technical considerations and performance characteristics of vibrating mesh nebulizers
Technical consideration | Performance characteristics vibrating mesh nebulizers | ||
|---|---|---|---|
Bayer Amikacin Inhale | Aerogen Aeroneb Solo | PARI eFlow | |
Mode of action | Breath synchronized (hand-held = continuous nebulization) | Continuous nebulization | Breath enhanced |
Delivered dose | On-vent: 35–58 %; hand-held: 35–64 % [54] | 31–44 % [73] | |
Delivery time | Timing depends on patient and flow rate but has been reported to be 36 ± 16 (on-vent) and 15 ± 5 (hand-held) [54] | Dependent on medication but suggested to be around 7–10 min with 3 mL albuterol [71, 72] | Dependent on medication [63] |
Humidification | Humidification does not affect delivered dose of amikacin Recommended to remove HME device | Recommended to turn humidification off during delivery Remove HME as per manufacturer’s instructions | Humidification can be left on during delivery [66] |