From: The passive leg raising test to guide fluid removal in critically ill patients
Baseline | PLR (% change from baseline) | H1 | H2 | H3 | H4 | H5 | H6 | ||
---|---|---|---|---|---|---|---|---|---|
Number of patients at this time of the study | |||||||||
Patients without intradialytic hypotension | 26 | 26 | 26 | 26 | 25 | 23 | 8 | 7 | |
Patients with intradialytic hypotension | 13 | 13 | 13 | 9 | 5 | 2 | 0 | 0 | |
Heart rate (beats/min) | |||||||||
Patients without intradialytic hypotension | 93 [81–106] | 91 [79–101] | 0 [-2–1] | 90 [78–104] | 93 [78–103] | 91 [81–109] | 89 [78–107] | 97 [84–110] | 97 [94–119.00] |
Patients with intradialytic hypotension | 95 [90–98] | 95 [91–97] | 0 [1–1] | 91 [90–99] | 93 [73–102] | 89 [68–96] | 103 [96–111] | – | – |
Systolic arterial pressure (mmHg)* | |||||||||
Patients without intradialytic hypotension | 130 [120–151] | 134 [120–151] | 0 [0–3] | 125 [115–153] | 131 [118–148] | 128 [113–150] | 130 [110–149] | 117 [109–140] | 97 [94–119.00] |
Patients with intradialytic hypotension | 117 [102–131] | 120 [111–130] | 0 [0–3] | 112 [108–120] | 105 [102–108] | 108 [98–109] | 105 [92–119] | – | – |
Mean arterial pressure (mmHg) | |||||||||
Patients without intradialytic hypotension | 87 [82–98] | 90 [82–102] | 0 [-1–3] | 84 [78–95] | 90 [80–96] | 90 [76–96] | 86 [79–94] | 82 [74–92] | 67 [66–61.00] |
Patients with intradialytic hypotension | 87 [79–89] | 88 [82–92] | 2 [-1–5] | 81 [69–84] | 75 [69–83] | 68 [68–85] | 78 [72–84] | – | – |
Diastolic arterial pressure (mmHg)* | |||||||||
Patients without intradialytic hypotension | 64 [57–73] | 64 [58–75] | 0 [0–4] | 62 [56–69] | 65 [57–71] | 65 [52–72] | 61 [58–67] | 63 [56–68] | 57 [53–60.00] |
Patients with intradialytic hypotension | 65 [63–71] | 68 [60–71] | 1 [0–4] | 63 [46–70] | 59 [54–63] | 51 [48–61] | 62 [21–63] | – | – |
Cardiac index (L/min/m2)* | |||||||||
Patients without intradialytic hypotension | 3.5 [2.7–4.2] | 3.6 [2.9–4.1] | 2 [0–5] | 3.4 [2.6–3.8] | 3.1 [2.6–3.8] | 3.4 [2.2–3.8] | 3.1 [2.6–3.7] | 2.8 [2.5–3.4] | 2.6 [2.4–2.9] |
Patients with intradialytic hypotension | 3.0 [2.3–3.2] | 3.5 [3.1–4.0] | 15 [11–36] | 2.4 [1.7–2.8] | 2.3 [1.6–2.3] | 1.5 [1.4–2.1] | 1.9 [1.5–2.2] | – | – |
Global end-diastolic volume (mL/m2) | |||||||||
Patients without intradialytic hypotension | 765 [654–834] | 716 [609–786] | 685 [597–786] | 707 [588–846] | 712 [626–772] | 812 [652–921] | 865 [632–935] | ||
Patients with intradialytic hypotension | 700 [626–749] | 693 [570–709] | 641 [584–710] | 500 [500–663] | 539 [503–574] | – | – | ||
Extravascular lung water (mL/kg) | |||||||||
Patients without intradialytic hypotension | 11 [8–16] | 11 [8–15] | 9 [8–15] | 8 [8–14] | 8 [7–12] | 7 [6–9] | 9 [6–11] | ||
Patients with intradialytic hypotension | 8 [7–14] | 8 [7–15] | 8 [7–13] | 6 [5–7] | 5 [5–6] | – | – | ||
Cardiac function index (min−1) | |||||||||
Patients without intradialytic hypotension | 4.5 [3.5–5.4] | 4.4 [4.1–5.2] | 4.7 [3.9–5.6] | 4.1 [3.8–5.1] | 4.8 [4.0–5.0] | 4.0 [3.8–4.1] | 3.5 [3.0–4.4] | ||
Patients with intradialytic hypotension | 4 [3.5–5.0] | 4.1 [2.9–5.0] | 3.4 [2.5–4.1] | 4.3 [3.4–5.2] | 4.3 [4.0–4.5] | – | – | ||
Volume of fluid removed (mL) | |||||||||
Patients without intradialytic hypotension | – | – | 1000 [660–1000] | 2000 [1320–2000] | 3000 [1860–3000] | 4000 [2480–4000] | 3300 [2900–5000] | 4980 [3240–6000] | |
Patients with intradialytic hypotension | – | – | 660 [500–1000] | 2000 [1320–2000] | 1980 [1500–3000] | 3000 [2500–3500] | – | – | |
Body temperature | |||||||||
Patients without intradialytic hypotension | 37.6 [37.0–38.3] | – | 37.6 [37.0–38.3] | 37.6 [36.9–38.3] | 37.3 [36.6–38.0] | 37.2 [36.4–38.0] | 37.2 [36.8–37.8] | 37.2 [36.8–37.8] | |
Patients with intradialytic hypotension | 37.5 [36.9–37.9] | – | 37.5 [36.9–37.9] | 37.4 [36.7–37.9] | 37.6 [36.6–38.2] | 37.0 [36.8–37.3] | – | – |