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Table 4 Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of PCT and Presepsin and their combinations for severe sepsis and septic shock and for pneumonia diagnoses

From: Diagnostic and prognostic value of soluble CD14 subtype (Presepsin) for sepsis and community-acquired pneumonia in ICU patients

 

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

SS and SSh

 PCTa

80

59

82

57

 Presepsinb

90

55

82

71

 PCT and Presepsin

75

68

85

55

Pneumonia

 PCTa

69

80

93

40

 Presepsinc

81

80

94

52

 PCT and Presepsin

62

93

97

62

  1. SS severe sepsis, SSh septic shock, PPV positive predictive value, NPV negative predictive value
  2. aCutoff value for PCT at 0.5 ng/mL
  3. bCutoff value for Presepsin at 466 pg/mL
  4. cCutoff value for Presepsin at 588 pg/mL