Skip to main content

Table 1 Characteristics of 295 admissions with hypoxic hepatitis

From: Outcome and features of acute kidney injury complicating hypoxic hepatitis at the medical intensive care unit

Parameter  
Number of patients 295
Admission parameters
 Age (years), median (IQR) 63 (51–72)
 Females, n (%) 94 (32 %)
 SAPS II, median (IQR) 62 (45–79)
 SOFA, median (IQR) 11 (8–15)
 Heart rate (bpm), median (IQR) 81 (65–104)
 MAP (mmHg), median (IQR) 68 (57–82)
 Respiratory rate (breaths/min), median (IQR) 20 (16–25)
 Body temperature (°C), median (IQR) 36.5 (35.5–37.5)
 pH, median (IQR) 7.30 (7.20–7.40)
 AST (IU/l), median (IQR) 366 (73–1265)
 ALT (IU/l), median (IQR) 139 (39–706)
 LDH (IU/l), median (IQR) 599 (360–1523)
 INR, median (IQR) 1.4 (1.2–1.9)
Peak values
 AST (IU/l), median (IQR) 2457 (1168–5605)
 ALT (IU/l), median (IQR) 1151 (534–2620)
 LDH (IU/l), median (IQR) 2439 (1334–4999)
 INR, median (IQR) 1.8 (1.4–2.7)
Underlying condition
 Cardiogenic shock, n (%) 130 (44 %)
 Septic shock, n (%) 106 (36 %)
 Mixed septic/cardiogenic shock, n (%) 3 (1 %)
 Hemorrhagic shock, n (%) 8 (3 %)
Therapy
 Mechanical ventilation, n (%) 225 (76 %)
 Vasopressor therapy, n (%) 231 (86 %)
 Renal replacement therapy, n (%) 122 (41 %)
Outcome parameters
 28-day mortality, n (%) 170 (58 %)
 ICU-LOS (days), median (IQR) 7 (2–14)
  1. SAPS II simplified acute physiology score, SOFA sequential organ failure assessment, MAP mean arterial pressure, AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, ICU-LOS length of stay at the ICU, IQR interquartile range