Toe-to-room temperature gradient correlates with tissue perfusion and predicts outcome in selected critically ill patients with severe infections

Annals of Intensive Care

Table 2 Haemodynamic parameters of patients with severe sepsis and septic shock

Haemodynamic parameters at H6	Severe sepsis (n = 40)	Septic shock (n = 63)	P value
N	40	63	–
SOFA score	4 [3; 5]	12 [8; 14]	<0.001
MAP (mmHg)	75 [69; 84]	71 [67; 76]	NS
CI (L/min/m²)	2.7 [2.1; 3.4]	2.5 [2.0; 3.0]	NS
Urinary output (mL/kg/h)	1.0 [0.7; 1.4]	0.5 [0.1; 1.2]	<0.001
Lactate level (mmol/L)	1.2 [0.9; 1.9]	2.3 [1.4; 6.0]	<0.001
Index CRT (s)	1.6 [1.0; 2.3]	2.5 [1.7; 4.5]	0.002
Knee CRT (s)	2.2 [1.2; 2.9]	4.2 [2.8; 5.8]	<0.001
Mottling score (n) ^a
0–1	35	35	0.005
2–3	2	12
4–5	0	6

Data are expressed as number or median and IQRs
SOFA Sequential Organ Failure Assessment, MAP mean arterial pressure, CI cardiac index, CRT capillary refill time
^aPatients with dark skin were excluded