| Before | After |
p
|
---|
pH | 7.43 (7.40–7.46) | 7.46 (7.43–7.48) | 0.014 |
PaCO2 (mmHg) | 40 (38–43) | 41 (39–45) | 0.36 |
HCO3
− (mmol/L) | 26.6 (25.3–28.3) | 29.0 (28.5–30.6) | 0.002 |
BE (mmol/L) | 2.2 (1.5–4.6) | 5.5 (4.2–6.8) | 0.001 |
SID (mEq/L) | 31 (31–33) | 35 (34–36) | 0.012 |
Na+ (mEq/L) | 139 (135–142) | 140 (137–141) | 0.36 |
K+ (mEq/L) | 3.7 (3.5–4.4) | 3.8 (3.5–4.2) | 0.92 |
Cl− (mEq/L) | 110 (106–111) | 106 (105–109) | 0.009 |
Lactate (mEq/L) | 0.9 (0.7–2.2) | 1.0 (0.7–1.2) | 0.24 |
- Data are reported as median value and interquartile ranges before the first and after the last intravenous administration of furosemide for the subgroup of patients receiving multiple administrations (multiple-dose
group, n = 11). Total dose of furosemide averaged 38±17 mg, and observation period lasted 22 ± 13 h. Paired t test or Wilcoxon signed rank test was performed, as appropriate
-
PaCO
2
arterial partial pressure of carbon dioxide, HCO
−
3
bicarbonate concentration, BE base excess, SID strong ion difference, Na
+ sodium concentration, K
+ potassium concentration, Cl
− chloride concentration