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Table 3 Plasmatic acid–base equilibrium before and after furosemide administration

From: Real-time urinary electrolyte monitoring after furosemide administration in surgical ICU patients with normal renal function

 

Before

After

p

pH

7.43 (7.40–7.46)

7.46 (7.43–7.48)

0.014

PaCO2 (mmHg)

40 (38–43)

41 (39–45)

0.36

HCO3 − (mmol/L)

26.6 (25.3–28.3)

29.0 (28.5–30.6)

0.002

BE (mmol/L)

2.2 (1.5–4.6)

5.5 (4.2–6.8)

0.001

SID (mEq/L)

31 (31–33)

35 (34–36)

0.012

Na+ (mEq/L)

139 (135–142)

140 (137–141)

0.36

K+ (mEq/L)

3.7 (3.5–4.4)

3.8 (3.5–4.2)

0.92

Cl− (mEq/L)

110 (106–111)

106 (105–109)

0.009

Lactate (mEq/L)

0.9 (0.7–2.2)

1.0 (0.7–1.2)

0.24

  1. Data are reported as median value and interquartile ranges before the first and after the last intravenous administration of furosemide for the subgroup of patients receiving multiple administrations (multiple-dose group, n = 11). Total dose of furosemide averaged 38±17 mg, and observation period lasted 22 ± 13 h. Paired t test or Wilcoxon signed rank test was performed, as appropriate
  2. PaCO 2 arterial partial pressure of carbon dioxide, HCO − 3 bicarbonate concentration, BE base excess, SID strong ion difference, Na + sodium concentration, K + potassium concentration, Cl − chloride concentration