Immature/total granulocyte ratio improves early prediction of neurological outcome after out-of-hospital cardiac arrest: the MyeloScore study

Annals of Intensive Care

Table 1 Baseline characteristics of the patients included in the development cohort

Variable	All patients (n = 204)
Patient demographics
Age (years)	58 [48–67]
Male sex, n (%)	156 (76.5)
Body mass index (kg/m²)	26 [23–28]
Charlson comorbidity index	0 [0–1]
OHCA characteristics
Location of OHCA, n (%)
Public place	65 (32)
Private place	139 (68)
Witnessed OHCA, n (%)	168 (82.5)
Bystander CPR, n (%)	110 (54)
Arrest rhythm, n (%)
Initial VF/VT	91 (44.6)
PEA/asystole	113 (55.5)
No-flow time (min)	4 [0–10]
Low-flow time (min)	20 [15–30]
On-scene epinephrine dose (mg)	2 [1–5]
Laboratory values at ICU admission
Arterial lactate (mmol/L)	4 [2–7.5]
Creatinine (µmol/L)	103 [84–142]
Troponin (µg/L)	1 [0–11]
Leukocytes (g/L)	15 [11–19.5]
Neutrophils (g/L)	12 [8–16]
I/T-G ratio (%)	0.9 [0.5–2]
Severity scores
SOFA on day 1	11 [8–13]
SAPS II on day 1	69.5 [59–80]
OHCA score	29.5 [6.5–43.5]
CAHP score	170 [142–200]
Hospital data
Admission temperature (°C)	35 [34–35.5]
Therapeutic hypothermia, n (%)	130 (63)
Early coronary angioplasty, n (%)	62 (30.5)
Postresuscitation shock, n (%)	107 (52.5)
Hospital length of stay (days)	8 [3–17]

Data are expressed in median [IQR] and n (%)
No-flow time is the time between collapse and base life support. Low-flow time is the time between base life support and return of spontaneous circulation
CPC cerebral performance category OHCA out-of-hospital cardiac arrest, CPR cardiopulmonary resuscitation, VF/VT ventricular fibrillation/ventricular tachycardia, PEA pulseless electrical activity, I/T-G ratio of immature over total granulocytes in peripheral blood, SOFA Sequential Organ Failure Assessment, SAPS II, Simplified Acute Physiology Score version II