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Table 4 Analysis of association between transfusion products and nosocomial infection in separate models

From: Transfusion of platelets, but not of red blood cells, is independently associated with nosocomial infections in the critically ill

Blood product

Logistic regression

Cox regression

Odds ratio

95 % CI

p value

Hazard

95 % CI

p value

Red blood cells

 RBC transfusiona

1.977

1.535–2.547

<0.001

1.143

0.906–1.442

0.259

 RBC unitsa

1.044

1.026–1.063

<0.001

1.014

1.000–1.028

0.053

Fresh-frozen plasma

 FFP transfusionb

2.510

1.978–3.186

<0.001

1.362

1.101–1.685

0.004

Platelets

 Platelet transfusionc

2.530

1.998–3.205

<0.001

1.463

1.184–1.806

<0.001

  1. FFP fresh-frozen plasma, RBC red blood cells
  2. aCorrected for exposure bias (for RBC transfusion) summarized in propensity score including trauma, malignancy, admission type, APACHE IV score and sepsis. Also corrected for confounders including APACHE predicted length of stay and mechanical ventilation
  3. bCorrected for exposure bias (for FFP transfusion) summarized in propensity score including admission type, APACHE IV score and sepsis. Also corrected for confounders including APACHE predicted length of stay and mechanical ventilation
  4. cCorrected for exposure bias (for platelet transfusion) summarized in propensity score including admission type, malignancy, APACHE IV score and sepsis. Also corrected for confounders including APACHE predicted length of stay and mechanical ventilation