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Table 1 Demographic characteristics of patients treated with PMX-HP

From: Polymyxin-B hemoperfusion in septic patients: analysis of a multicenter registry

Demographic characteristics

N 357

Age, years, mean ± SD

63 (51–72)

Gender, male

240 (67.2)

SAPS II at admission, mean ± SD

50.3 ± 19.2

APACHE II at admission, mean ± SD

21.8 ± 7.2

SOFA at admission, mean ± SD

10.9 ± 3.5

Incidence of shock

305 (85.4)

Source of sepsis

 Abdominal

157 (44)

 Pulmonary

63 (17.6)

 Urinary

16 (4.5)

 Cardiac

23 (6.4)

 Trauma

19 (5.3)

 Othera

79 (22)

Patients without microbiological cultures N (%)

139 (38.9)

Patients with microbiological cultures

218 (61.1)

 Negative microbiological cultures

41 (18.8)

 Positive microbiological cultures

177 (81.1)

 Gram positive only

17 (7.8)

 Gram negative only

81 (37.2)

 Fungi only

13 (6.0)

 Mixed including gram negatives

51 (23.4)

 Mixed not including gram negatives

8 (3.7)

Patients with endotoxin activity assay, N (%)

132 (37)

 Abdominal

47 (35.6)

 Non-abdominal

85 (64.4)

 Without microbiology data

33 (25)

 Negative cultures

12 (9)

 Gram positive only

7 (5.3)

 Gram negative only

43 (32.6)

 Fungi only

14 (10.6)

 Mixed including gram negatives

21 (15.9)

 Mixed not including gram negatives

3 (2.2)

Patients with 2 treatments, N (%)

219 (61)

Patients with 1 treatment, N (%)

138 (39)

28 days survival

180 (54.5)

ICU survival

192 (55.2)

Hospital survival

172 (50)

  1. Data are expressed as N (%) apart from otherwise indicated
  2. aOther includes soft tissue infections, CVC-related infections, meningitides