From: Polymyxin-B hemoperfusion in septic patients: analysis of a multicenter registry
Demographic characteristics | N 357 |
---|---|
Age, years, mean ± SD | 63 (51–72) |
Gender, male | 240 (67.2) |
SAPS II at admission, mean ± SD | 50.3 ± 19.2 |
APACHE II at admission, mean ± SD | 21.8 ± 7.2 |
SOFA at admission, mean ± SD | 10.9 ± 3.5 |
Incidence of shock | 305 (85.4) |
Source of sepsis | |
Abdominal | 157 (44) |
Pulmonary | 63 (17.6) |
Urinary | 16 (4.5) |
Cardiac | 23 (6.4) |
Trauma | 19 (5.3) |
Othera | 79 (22) |
Patients without microbiological cultures N (%) | 139 (38.9) |
Patients with microbiological cultures | 218 (61.1) |
Negative microbiological cultures | 41 (18.8) |
Positive microbiological cultures | 177 (81.1) |
Gram positive only | 17 (7.8) |
Gram negative only | 81 (37.2) |
Fungi only | 13 (6.0) |
Mixed including gram negatives | 51 (23.4) |
Mixed not including gram negatives | 8 (3.7) |
Patients with endotoxin activity assay, N (%) | 132 (37) |
Abdominal | 47 (35.6) |
Non-abdominal | 85 (64.4) |
Without microbiology data | 33 (25) |
Negative cultures | 12 (9) |
Gram positive only | 7 (5.3) |
Gram negative only | 43 (32.6) |
Fungi only | 14 (10.6) |
Mixed including gram negatives | 21 (15.9) |
Mixed not including gram negatives | 3 (2.2) |
Patients with 2 treatments, N (%) | 219 (61) |
Patients with 1 treatment, N (%) | 138 (39) |
28 days survival | 180 (54.5) |
ICU survival | 192 (55.2) |
Hospital survival | 172 (50) |