Assessment and predictors of physical functioning post-hospital discharge in survivors of critical illness

Annals of Intensive Care

Table 4 Summary of predictors of muscle strength and physical functioning at 3 months after hospital discharge

Variable n = 50^a	6-Minute walk test	Grip	Triceps	Biceps	Hamstrings	Quadriceps	Ankle dorsiflexors
ICU LOS, days	−0.003 (0.041)	−0.002 (0.85)	−0.010 (0.305)	−0.005 (0.537)	−0.001 (0.806)	0.000 (0.922)	−0.001 (0.685)
Hospital LOS, days	−0.003 (0.079)	−0.001 (0.965)	0.002 (0.727)	0.003 (0.498)	0.000 (0.969)	0.003 (0.274)	0.001 (0.755)
Mechanical ventilation, days	−0.004 (0.045)	−0.001 (0.905)	−0.009 (0.378)	−0.004 (0.610)	−0.001 (0.899)	0.001 (0.809)	−0.001 (0.742)
Presence of sepsis	−0.168 (0.029)	−0.389 (0.009)	−0.328 (0.045)	−0.315 (0.033)	−0.328 (0.016)	−0.134 (0.262)	−0.197 (0.049)
APACHE II score	−0.003 (0.642)	−0.002 (0.868)	−0.008 (0.515)	0.003 (0.802)	0.003 (0.755)	0.011 (0.212)	0.006 (0.397)
SOFA score	0.011 (0.257)	0.022 (0.229)	0.021 (0.325)	0.027 (0.167)	0.020 (0.219)	0.019 (0.174)	0.017 (0.154)
Functional Comorbidity Index	−0.019 (0.593)	−0.070 (0.247)	−0.111 (0.114)	−0.050 (0.437)	−0.000 (0.998)	0.013 (0.803)	−0.044 (0.274)
Any corticosteroid use^b	−0.215 (0.019)	−0.304 (0.092)	−0.382 (0.062)	−0.359 (0.052)	−0.320 (0.047)	−0.222 (0.137)	−0.221 (0.058)

ICU intensive care unit, LOS length of stay, APACHE Acute Physiology and Chronic Health Evaluation, SOFA Sequential Organ Failure Assessment, 6MWT 6-min walk test
^aβ-Coefficients (p value) modeled as univariate regression analyses. 6MWT and muscle strength modeled as percent predicted. β-Coefficients represent the percent change in the physical functioning variable per unit change in exposure variable
^bAlso analyzed using cumulative ICU and average daily corticosteroid dose with no significance found