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Table 1 Evidence grading and recommendations formulation

From: Management of neutropenic patients in the intensive care unit (NEWBORNS EXCLUDED) recommendations from an expert panel from the French Intensive Care Society (SRLF) with the French Group for Pediatric Intensive Care Emergencies (GFRUP), the French Society of Anesthesia and Intensive Care (SFAR), the French Society of Hematology (SFH), the French Society for Hospital Hygiene (SF2H), and the French Infectious Diseases Society (SPILF)

Risk of bias and grade Type of recommendation Formulation
Low: Grade 1 Positive recommendation + Should be
High level of evidence Negative recommendation − Should not be
Intermediate to high: Grade 2 Positive recommendation + Should probably be
Intermediate to low level of evidence Negative recommendation − Should probably not be
High: expert opinion Positive recommendation + Should probably be (expert opinion)
No available data Negative recommendation − Should probably not be (expert opinion)