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Table 1 Baseline characteristics of 439 survivors and non-survivors with the acute respiratory distress syndrome in the Netherlands

From: External validation of the APPS, a new and simple outcome prediction score in patients with the acute respiratory distress syndrome

  Survivors (N = 252) Non-survivors (N = 187; 43 %) P
Gender, male, N (%) 163 (64.7) 120 (64.2) 0.92
Age, mean ± SD 58.5 ± 15.4 63.1 ± 12.7 0.001
Cause of ARDS, N (%)
 Pneumonia 154 (61.1) 115 (61.5) 1.0
 Aspiration 25 (9.9) 16 (8.6) 0.76
 Other pulmonary 2 (0.8) 1 (0.5) 1.0
 Sepsis 144 (57.1) 132 (70.6) 0.003
 Trauma 38 (15.1) 15 (8.0) 0.029
 Pancreatitis 2 (0.8) 6 (3.2) 0.069
 Other non-pulmonary 29 (11.5) 17 (9.1) 0.43
Disease severity, mean ± SD
 APACHE IV 85.5 ± 27 102.7 ± 30.7 <0.001
 SOFA score 8.6 ± 3.2 10.1 ± 4.1 <0.001
Physiological parameters, mean ± SD
 pH, median ± IQR 7.4, 7.4–7.5 7.4, 7.3–7.4 0.001
 PaCO2 42.1 ± 9 44.4 ± 12.1 0.039
 PaO2/FiO2 126.8 ± 38.3 127.7 ± 43.1 0.81
 Respiratory system compliance 28.9 ± 15.6 37.4 ± 20.9 <0.001
Ventilation parameters, mean ± SD
 Tidal volume (ml/kg PBW) 7.7 ± 2 7.5 ± 1.7 0.38
 FiO2 53.2 ± 12.9 56.7 ± 16.7 0.017
 Respiratory rate 22 ± 7 25 ± 8 <0.001
 PEEP (cmH2O) 10.4 ± 3.6 10.9 ± 4 0.2
 P max (cmH2O) 26.2 ± 7.9 28.2 ± 9.4 0.018