Entire cohort n = 10,165 | Admission type | ||||
---|---|---|---|---|---|
Medical n = 3505 (34.5 %) | Elective surgery | Emergency surgery and trauma n = 2109 (20.7 %) | |||
Cardiac | Other | ||||
n = 2357 (23.2 %) | n = 2194 (21.6 %) | ||||
Demographic data | |||||
Female (%) | 3861 (38.0 %) | 1369 (39.1 %) | 754 (32.0 %) | 914 (41.7 %) | 824 (39.1 %) |
Age (mean in years ± SD) | 62.7 ± 15.3 | 63.0 ± 15.0 | 68.7 ± 10.7 | 60.1 ± 14.4 | 58.1 ± 17.0 |
SAPS-3 (mean ± SD) | 49.5 ± 16.2 | 61.3 ± 14.5 | 40.5 ± 8.9 | 36.8 ± 10.9 | 53.1 ± 14.1 |
Comorbidities [n (%)] | |||||
Chronic kidney disease | 1317 (12.9 %) | 600 (17.1 %) | 297 (12.6 %) | 187 (8.5 %) | 233 (11.1 %) |
Heart failure | 2931 (28.8 %) | 963 (27.19 %) | 1392 (59.1 %) | 217 (9.9 %) | 369 (17.5 %) |
COPD | 1120 (11.0 %) | 490 (14.0 %) | 228 (9.7 %) | 243 (11.1 %) | 159 (7.5 %) |
Diabetes mellitus | 1743 (17.2 %) | 671 (19.1 %) | 489 (20.8 %) | 290 (13.2 %) | 293 (13.9 %) |
Liver cirrhosis | 348 (3.4 %) | 202 (5.8 %) | 10 (0.4 %) | 63 (2.9 %) | 73 (3.5 %) |
Malignancy | 440 (4.3 %) | 96 (2.7 %) | 11 (0.5 %) | 283 (12.9 %) | 50 (2.37 %) |
Outcome [n (%)] | |||||
30-day ICU mortality | 929 (9.1 %) | 622 (17.8 %) | 54 (2.3 %) | 44 (2.0 %) | 209 (9.9 %) |
Hospital mortalitya | 1661 (19.7 %) | 1061 (37.6 %) | 99 (4.5 %) | 173 (10.0 %) | 327 (19.1 %) |
Covariates of interest on day of admission (mean ± SD) | |||||
Chloride (mmol/L) | 107.3 ± 5.5 | 104.6 ± 6.0 | 111.3 ± 3.4 | 107.6 ± 3.9 | 107.1 ± 5.3 |
SIDa (mEq/L) | 42.9 ± 3.6 | 44.3 ± 4.0 | 41.2 ± 3.0 | 42.4 ± 2.9 | 43.1 ± 3.4 |
Biochemistry and physicochemical covariates on day of admission (mean ± SD) | |||||
Sodium (mmol/L) | 140.1 ± 4.9 | 138.8 ± 5.4 | 142.3 ± 3.7 | 139.9 ± 3.7 | 140.1 ± 5.2 |
Lactate (mmol/L) | 2.4 ± 2.1 | 2.4 ± 2.5 | 2.8 ± 1.6 | 1.7 ± 1.1 | 2.5 ± 2.4 |
Albumin (g/L) | 27.2 ± 7.0 | 28.5 ± 6.9 | 23.0 ± 5.0 | 28.5 ± 6.1 | 28.2 ± 8.0 |
SIDa incl. lactate (mEq/L) | 40.6 ± 3.9 | 42.0 ± 4.3 | 38.4 ± 2.9 | 40.7 ± 3.0 | 40.7 ± 3.6 |
SIDe (mEq/L) | 33.7 ± 4.9 | 34.8 ± 5.8 | 30.6 ± 3.3 | 34.7 ± 3.5 | 34.0 ± 4.6 |
SIG (mEq/L) | 6.9 ± 3.5 | 7.2 ± 3.8 | 7.8 ± 2.9 | 5.9 ± 3.0 | 6.6 ± 3.7 |