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Table 3 Logistic regression models in the total ICU population excluding patients admitted after elective cardiac surgery

From: Impact of chloride and strong ion difference on ICU and hospital mortality in a mixed intensive care population

  Outcome: 30-day mortalitya (n = 6480) Outcome: hospital mortalityb (n = 5184)
n % outcome (%) Odds ratio (95 % CI) versus normochloremia p value n % outcome (%) Odds ratio (95 % CI) versus normochloremia p value
Chloride category
Normochloremia 3382 10.2    2707 24.3   
Hypochloremia 434 16.4 1.02 (0.71–1.48) 0.91 329 43.8 1.55 (1.13–2.13) 0.007
Moderate hyperchloremia 1456 8.5 1.16 (0.88–1.51) 0.30 1188 18.4 0.96 (0.77–1.20) 0.72
Severe hyperchloremia 1208 14.6 1.81 (1.32–2.50) <0.001 960 29.0 1.49 (1.14–1.96) 0.003
  n % outcome (%) Odds ratio (95 % CI) versus intermediate SIDa p value n % outcome (%) Odds ratio (95 % CI) versus intermediate SIDa p value
SIDa category
Intermediate SIDa 2982 9.6    2382 20.5   
Low SIDa 1598 9.4 0.89 (0.68–1.16) 0.40 1260 21.5 0.94 (0.70–1.15) 0.60
High SIDa 1900 14.6 1.05 (0.83–1.32) 0.71 1542 34.9 1.35 (1.11–1.65) 0.002
  Area under ROC 86.7 %    Area under ROC 83.5 %
Maximal VIF 2.26   Maximal VIF 2.39
Tolerance 0.68   Tolerance 0.68
  1. SIDa apparent strong ion difference (excl. lactate), ROC receiver under operating characteristics curve, VIF variance inflation factor
  2. aConfounders adjusted for in the model: sodium (high vs. normal*, low vs. normal*), SAPS-3, admission reason, RIFLEcrea*, RIFLEurine, lactate, heart failure*, COPD*, pCO2* (low, normal, high), albumin, SIG, potentiometry type* (*p > 0.05)
  3. bConfounders adjusted for in the model: sodium (high vs. normal*, low vs. normal*), SAPS-3, admission reason, RIFLEcrea, RIFLEurine, lactate, heart failure, COPD, pCO2* (low, normal, high), albumin, SIG*, potentiometry type (*p > 0.05)