Predictive factors of bleeding events in adults undergoing extracorporeal membrane oxygenation

Annals of Intensive Care

Table 3 Factors independently associated with bleeding in multivariable analysis

Variable	Adjusted odds ratio	95 % confidence interval	P
Previous-day aPTT^a
≥46 and ≤55 s	1.35	0.73–2.49	0.33
≥56 and ≤69 s	1.45	0.75–2.82	0.26
≥70 s	3.00	1.64–5.47	<0.01
Previous-day anticoagulation	0.40	0.24–0.66	<0.01
APACHE III score	1.01	1.01–1.02	0.01
Post-surgical ECMO	3.04	1.62–5.69	<0.01

Analysis includes 1125 days with complete data
aPTT activated partial thromboplastin time, APACHE III score Acute Physiology and Chronic Health Evaluation III score
^aaPTT < 46 s is the reference