Table 2 Comparison of patients with and without undetermined ARF etiology (N (%)—median [IQR 25–75])
(N (%)—median [IQR 25–75]) | Undetermined diagnosis (n = 78) | Others (n = 526) | p value |
|---|---|---|---|
Age (year) | 60.5 [52–72] | 60 [50–70] | 0.53 |
Malignancy | |||
Acute myeloid leukemia | 20 (25.7%) | 148 (28.1%) | 0.26 |
Non-Hodgkin lymphoma | 21 (26.9%) | 143 (27.1%) | |
Myeloma | 18 (23.1%) | 63 (12%) | |
Chronic lymphocytic leukemia | 8 (10.3%) | 47 (9%) | |
Acute lymphoblastic leukemia | 3 (3.8%) | 35 (6.6%) | |
Myelodysplastic syndrome | 4 (5.1%) | 26 (5%) | |
Hodgkin’s disease | 1 (1.3%) | 17 (3.2%) | |
Others | 3 (3.8%) | 47 (9%) | |
Disease status at admission | |||
Earliest phase | 19 (24.4%) | 189 (35.9%) | 0.09 |
Progression | 31 (39.7%) | 209 (39.7%) | |
Complete or partial remission | 23 (29.5%) | 115 (21.9%) | |
Unknown | 5 (6.4%) | 13 (2.5%) | |
Stem cell transplantation | |||
Autologous | 11 (14%) | 51 (9.7%) | 0.022 |
Allogeneic | 21 (26.9%) | 86 (16.3%) | |
Performance status 2–4 | 24 (31%) | 100 (19%) | 0.025 |
Delay of admission >24 h | 25 (32.1%) | 230 (43.7%) | 0.072 |
Neutropenia | 26 (33%) | 156 (30%) | 0.6 |
Respiratory rate at admission (/min) | 35 [28–40] | 32 [26–38] | 0.13 |
Invasive mechanical ventilation at day 1 | 33 (42.3%) | 217 (41.3%) | 0.88 |
SOFA score >7 | 38 (48.7%) | 232 (44.1%) | 0.39 |