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Table 2 Comparison of patients with and without undetermined ARF etiology (N (%)—median [IQR 25–75])

From: Increased mortality in hematological malignancy patients with acute respiratory failure from undetermined etiology: a Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologie (Grrr-OH) study

(N (%)—median [IQR 25–75]) Undetermined diagnosis (n = 78) Others (n = 526) p value
Age (year) 60.5 [52–72] 60 [50–70] 0.53
Malignancy    
 Acute myeloid leukemia 20 (25.7%) 148 (28.1%) 0.26
 Non-Hodgkin lymphoma 21 (26.9%) 143 (27.1%)  
 Myeloma 18 (23.1%) 63 (12%)  
 Chronic lymphocytic leukemia 8 (10.3%) 47 (9%)  
 Acute lymphoblastic leukemia 3 (3.8%) 35 (6.6%)  
 Myelodysplastic syndrome 4 (5.1%) 26 (5%)  
 Hodgkin’s disease 1 (1.3%) 17 (3.2%)  
 Others 3 (3.8%) 47 (9%)  
Disease status at admission    
 Earliest phase 19 (24.4%) 189 (35.9%) 0.09
 Progression 31 (39.7%) 209 (39.7%)  
 Complete or partial remission 23 (29.5%) 115 (21.9%)  
 Unknown 5 (6.4%) 13 (2.5%)  
Stem cell transplantation    
 Autologous 11 (14%) 51 (9.7%) 0.022
 Allogeneic 21 (26.9%) 86 (16.3%)  
Performance status 2–4 24 (31%) 100 (19%) 0.025
Delay of admission >24 h 25 (32.1%) 230 (43.7%) 0.072
Neutropenia 26 (33%) 156 (30%) 0.6
Respiratory rate at admission (/min) 35 [28–40] 32 [26–38] 0.13
Invasive mechanical ventilation at day 1 33 (42.3%) 217 (41.3%) 0.88
SOFA score >7 38 (48.7%) 232 (44.1%) 0.39
  1. Results were expressed as median and 25th and 75th quartiles [Q1–Q3] for quantitative data and numbers and percentages for categorical data. Marginal association between single variables and outcome was assessed by Wilcoxon rank-sum tests for quantitative variables and Fisher’s exact test or Chi-square test with Yates continuity correction for categorical variables when Fisher’s exact test was computationally impossible
  2. CR complete remission, NA not available, PR partial remission, IQR inter-quartile range