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Annals of Intensive Care

Table 1 Characteristics of patients with and without non-occlusive mesenteric ischemia

From: Diagnosis of non-occlusive acute mesenteric ischemia in the intensive care unit

Characteristics

Definite NOMI (n = 92)

NOMI ruled out (n = 55)

p

Baseline characteristics

   

 Age (years)

75 (61–81)

66 (55–78)

0.02

 Male gender

41 (45%)

31 (56%)

0.18

 BMI (kg/m2)

24 (21–27)

26 (23–29)

0.15

 Comorbidities

   

  Diabetes

13 (14%)

16 (29%)

0.03

  Hypertension

50 (54%)

27 (49%)

0.61

  Smoking

43 (47%)

26 (47%)

1.0

  Coronary disease

26 (28%)

20 (36%)

0.36

  Peripheral vascular disease

14 (15%)

12 (22%)

0.37

  End-stage renal disease

7 (8%)

4 (7%)

1.0

  Atrial fibrillation

33 (36%)

12 (22%)

0.10

 Main diagnosis at ICU admission

  

0.90

  Severe sepsis or septic shock

41 (45%)

22 (40%)

 

  Cardiogenic shock

3 (3%)

4 (7%)

 

  Hypovolemic shock

14 (15%)

7 (13%)

 

  Hemorrhagic shock

9 (10%)

7 (13%)

 

  Acute kidney injury

3 (3%)

3 (5%)

 

  Cardiac arrest

13 (14%)

7 (13%)

 

  Cardiac surgery

9 (10%)

5 (9%)

 

 Illness severity at admission (points)

   

  SAPS II

70 (57–87)

74 (48–91)

0.75

  SOFA

8 (5–11)

8 (4–12)

0.78

Diagnosis of NOMI

   

 Time to diagnosis (days)a

3.9 (1.5–13.0)

4.7 (2.1–9.7)

0.68

 Concurrent anticoagulation

  

0.75

  Preventive

34 (37%)

17 (31%)

 

  Curative

19 (20.7%)

13 (23.6%)

 

 Concurrent antibiotic treatment

90 (97.8%)

46 (83.6%)

0.002

 SOFA (points)

10 (6–13)

9 (7–12)

0.97

 Clinical manifestations

   

  Lower digestive symptoms

56 (61%)

29 (53%)

0.39

  Upper digestive symptoms

38 (41%)

19 (35%)

0.49

 Bacteremia

20 (21.7%)

9 (16.4%)

0.43

 Serum laboratory results

   

  Bicarbonates (mmol/L)

16.0 (14.0–21.1)

17.0 (14.5–21.5)

0.83

  Arterial lactate (mmol/L)

5.6 (2.2–10.1)

6.3 (2.1–11.2)

0.60

  Creatinine (μmol/L)

159 (125–231)

132 (84–247)

0.29

  K+ (mmol/L)

4.6 (4.1–5.4)

4.5 (3.9–5.2)

0.46

  CPK, ×UNV

1.0 (0.4–5.6)

3.0 (7.8–9.1)

0.09

  LDH, ×UNV

4.9 (2.2–12.7)

7.5 (2.8–17.3)

0.35

  AST, ×UNV

7.8 (1.3–43.7)

3.0 (1.0–43.5)

0.30

  Leukocyte count (G/L)

14.1 (9.5–23.6)

15.3 (8–22.5)

0.96

  Hemoglobin (g/dL)

10.0 (8.9–11.3)

9.9 (8.9–11.2)

0.51

  Platelets (G/L)

120 (61–199)

117 (62–182)

0.94

ICU mortality

69 (76%)

27 (49%)

0.002

  1. Categorical variables are expressed as median (interquartile range)
  2. Lower digestive symptoms include hematochezia, melena and diarrhea. Upper digestive symptoms include vomiting, feeding intolerance and acute upper gastrointestinal bleeding
  3. BMI body mass index, NOMI non-occlusive mesenteric ischemia, ICU intensive care unit, SAPS II simplified acute physiology score II, SOFA sequential organ failure assessment, UNV upper normal value (IU/L)
  4. aTime from ICU admission to the first investigation of NOMI (CT-scan, surgery or endoscopy)
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