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Table 1 Characteristics of patients with and without non-occlusive mesenteric ischemia

From: Diagnosis of non-occlusive acute mesenteric ischemia in the intensive care unit

Characteristics Definite NOMI (n = 92) NOMI ruled out (n = 55) p
Baseline characteristics    
 Age (years) 75 (61–81) 66 (55–78) 0.02
 Male gender 41 (45%) 31 (56%) 0.18
 BMI (kg/m2) 24 (21–27) 26 (23–29) 0.15
 Comorbidities    
  Diabetes 13 (14%) 16 (29%) 0.03
  Hypertension 50 (54%) 27 (49%) 0.61
  Smoking 43 (47%) 26 (47%) 1.0
  Coronary disease 26 (28%) 20 (36%) 0.36
  Peripheral vascular disease 14 (15%) 12 (22%) 0.37
  End-stage renal disease 7 (8%) 4 (7%) 1.0
  Atrial fibrillation 33 (36%) 12 (22%) 0.10
 Main diagnosis at ICU admission    0.90
  Severe sepsis or septic shock 41 (45%) 22 (40%)  
  Cardiogenic shock 3 (3%) 4 (7%)  
  Hypovolemic shock 14 (15%) 7 (13%)  
  Hemorrhagic shock 9 (10%) 7 (13%)  
  Acute kidney injury 3 (3%) 3 (5%)  
  Cardiac arrest 13 (14%) 7 (13%)  
  Cardiac surgery 9 (10%) 5 (9%)  
 Illness severity at admission (points)    
  SAPS II 70 (57–87) 74 (48–91) 0.75
  SOFA 8 (5–11) 8 (4–12) 0.78
Diagnosis of NOMI    
 Time to diagnosis (days)a 3.9 (1.5–13.0) 4.7 (2.1–9.7) 0.68
 Concurrent anticoagulation    0.75
  Preventive 34 (37%) 17 (31%)  
  Curative 19 (20.7%) 13 (23.6%)  
 Concurrent antibiotic treatment 90 (97.8%) 46 (83.6%) 0.002
 SOFA (points) 10 (6–13) 9 (7–12) 0.97
 Clinical manifestations    
  Lower digestive symptoms 56 (61%) 29 (53%) 0.39
  Upper digestive symptoms 38 (41%) 19 (35%) 0.49
 Bacteremia 20 (21.7%) 9 (16.4%) 0.43
 Serum laboratory results    
  Bicarbonates (mmol/L) 16.0 (14.0–21.1) 17.0 (14.5–21.5) 0.83
  Arterial lactate (mmol/L) 5.6 (2.2–10.1) 6.3 (2.1–11.2) 0.60
  Creatinine (μmol/L) 159 (125–231) 132 (84–247) 0.29
  K+ (mmol/L) 4.6 (4.1–5.4) 4.5 (3.9–5.2) 0.46
  CPK, ×UNV 1.0 (0.4–5.6) 3.0 (7.8–9.1) 0.09
  LDH, ×UNV 4.9 (2.2–12.7) 7.5 (2.8–17.3) 0.35
  AST, ×UNV 7.8 (1.3–43.7) 3.0 (1.0–43.5) 0.30
  Leukocyte count (G/L) 14.1 (9.5–23.6) 15.3 (8–22.5) 0.96
  Hemoglobin (g/dL) 10.0 (8.9–11.3) 9.9 (8.9–11.2) 0.51
  Platelets (G/L) 120 (61–199) 117 (62–182) 0.94
ICU mortality 69 (76%) 27 (49%) 0.002
  1. Categorical variables are expressed as median (interquartile range)
  2. Lower digestive symptoms include hematochezia, melena and diarrhea. Upper digestive symptoms include vomiting, feeding intolerance and acute upper gastrointestinal bleeding
  3. BMI body mass index, NOMI non-occlusive mesenteric ischemia, ICU intensive care unit, SAPS II simplified acute physiology score II, SOFA sequential organ failure assessment, UNV upper normal value (IU/L)
  4. aTime from ICU admission to the first investigation of NOMI (CT-scan, surgery or endoscopy)