Prognostic value of procalcitonin in patients after elective cardiac surgery: a prospective cohort study

Annals of Intensive Care

Table 5 Data are expressed as AUC (area under the curve) with 95% confidence interval (CI)

	ROC analysis to predict delayed complications (n = 751)
	AUC	95% CI	p value	Cutoff	Likelihood ratio	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
Preoperative
Procalcitonin (ng/ml)	0.58	0.52–0.64	0.007	>0.05	2.32	28	88	30	87
Leukocytes (x10⁹/l)	0.57	0.52–0.63	0.02	>9.3	1.97	27	86	27	87
C-reactive protein (mg/l)	0.60	0.54–0.65	<0.001	>11.6	2.07	27	87	28	87
Postoperative
Procalcitonin (ng/ml)	0.90	0.87–0.94	<0.001	>2.95	21.83	73	97	82	95
Leukocytes (×10⁹/l)	0.62	0.56–0.67	<0.001	>13.7	1.82	35	81	25	87
C-reactive protein (mg/l)	0.53	0.48–0.59	0.24	>46.4	1.06	85	21	16	88

Different receiver operating characteristic (ROC) curves were constructed to evaluate the predictive power for delayed complications
PPV the positive predictive value, NPV the negative predictive