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Table 1 Characteristics of study patients (N = 2336) and comparison between patients with and without acute kidney injury

From: Three-year mortality in 30-day survivors of critical care with acute kidney injury: data from the prospective observational FINNAKI study

Characteristics Data available All
N = 2336
No AKI
N = 1528
AKI
N = 808
p value
Age (years) 2336 62.0 (49.0–72.0) 61.0 (47.0–71.0) 64.0 (53.0–73.8) <0.001
Gender (male) 2336 1479 (63.3) 951 (61.6) 538 (66.6) 0.019
Operative admission 2336 886 (37.9) 577 (37.8) 309 (38.2) 0.823
Emergency admission 2336 2007 (85.9) 1312 (85.9) 695 (86.0) 0.950
Pre-morbid functional performance 2331     0.002
 Normal   1246 (53.5) 858 (56.2) 388 (48.2)  
 Disabled to work but no need for assistance   803 (34.4) 500 (32.8) 303 (37.6)  
 Some assistance required   216 (9.3) 131 (8.6) 85 (10.6)  
 Totally dependent on assistance   66 (2.8) 37 (2.4) 29 (3.6)  
APACHE diagnosis main groups 2336     <0.001
 Respiratory   264 (11.3) 178 (11.6) 86 (10.6)  
 Metabolic   244 (10.4) 181 (11.8) 63 (7.8)  
 Neurological   110 (4.7) 100 (6.5) 10 (1.2)  
 Gastrointestinal, non-op   139 (6.0) 81 (5.3) 58 (7.2)  
 Gastrointestinal, post-op   204 (8.7) 119 (7.8) 85 (10.5)  
 Sepsis   126 (5.4) 61 (4.0) 65 (8.0)  
 Cardiovascular, non-op   244 (10.4) 155 (10.1) 89 (11.0)  
 Cardiovascular, post-op   400 (17.1) 240 (15.7) 160 (19.8)  
 Trauma, non-op   118 (5.1) 92 (6.0) 26 (3.2)  
Arteriosclerosis 2336 279 (11.9) 158 (10.3) 121 (15.0) 0.001
Chronic kidney disease 2336 134 (5.7) 53 (3.5) 81 (10.0) <0.001
Chronic obstructive pulmonary disease 2336 203 (8.7) 127 (8.3) 76 (9.4) 0.396
Diabetes mellitus 2332 507 (21.7) 297 (19.5) 210 (26.0) <0.001
Hypertension 2336 1072 (45.9) 630 (41.2) 442 (54.7) <0.001
Chronic liver failure 2336 70 (3,0) 43 (2.8) 27 (3.3) 0.524
Malignancy 2200 63 (2.9) 44 (3.0) 19 (2.5) 0.504
Rheumatoid disease 2336 100 (4.3) 63 (4.1) 37 (4.6) 0.593
Systolic heart failure 2336 233 (10.0) 142 (9.3) 91 (11.3) 0.146
Thrombophilia 2336 125 (5.4) 81 (5.3) 44 (5.4) 0.923
Total number of comorbidities 2175     <0.001
 None   882 (37.8) 627 (41.0) 255 (31.6)  
 One   627 (26.8) 432 (28.3) 195 (24.1)  
 Two   478 (20.5) 288 (18.8) 190 (23.5)  
 Three or more   349 (14.9) 181 (11.8) 168 (20.8)  
Vasoactive drugs 2336 1419 (60.7) 810 (53.0) 609 (75.4) <0.001
Mechanical ventilation 2336 1540 (65.9) 975 (63.8) 565 (69.9) 0.003
Severe sepsis at ICU 2336 645 (27.6) 326 (21.3) 319 (39.5) <0.001
SAPS II 2336 34.0 (26.0–44.0) 32.0 (24.0–41.0) 39.0 (31.0–49.0) <0.001
SAPS II without age and renal points 2305 20.0 (13.0–27.0) 19.0 (13.0–27.0) 21.0 (15.0–28.0) 0.001
  1. Categorical data are presented as an absolute number/count (percentage) and continuous data as median with IQR
  2. AKI acute kidney injury, APACHE Acute Physiology and Chronic Health Evaluation, ICU intensive care unit, non-op non-operative, post-op postoperative, SAPS Simplified Acute Physiology Score
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