Skip to main content

Table 2 Multivariable adjusted Cox proportional hazards model for time to death during the 3-year follow-up

From: Three-year mortality in 30-day survivors of critical care with acute kidney injury: data from the prospective observational FINNAKI study

Characteristic Hazard ratio (95% CI) p value
Age (years) 1.03 (1.03–1.04) <0.001
Gender (female) 0.82 (0.68–0.98) 0.047
Functional performancea (normal as the reference)   
 Disabled to work but no need for assistance 1.65 (1.32–2.08) <0.001
 Some assistance required 2.65 (2.00–3.54) <0.001
 Totally dependent on assistance 3.48 (2.32–5.22) <0.001
Comorbiditiesb   
  Arteriosclerosis 1.05 (0.81–1.37 0.703
  Chronic kidney disease 1.53 (1.23–2.07) 0.006
  Chronic obstructive pulmonary disease 1.63 (1.26–2.10) <0.001
  Diabetes mellitus 1.15 (0.92–1.43) 0.219
  Hypertension 0.85 (0.69–1.04) 0.125
  Chronic liver failure 2.90 (1.89–4.44) <0.001
  Malignancy 3.18 (2.18–4.62) <0.001
  Rheumatoid disease 1.87 (1.35–2.60) <0.001
  Systolic heart failure 0.96 (0.73–1.26) 0.774
  Thrombophilia 0.83 (0.57–1.20) 0.313
Operative admission 1.04 (0.84–1.30) 0.710
Emergency admission 1.65 (1.16–2.33) 0.005
SAPS without age and renal points (per point)c 1.00 (0.99–1.01) 0.646
Vasoactive drugs 1.12 (0.90–1.39) 0.296
Severe sepsis 1.09 (0.89–1.33) 0.422
Acute kidney injury 1.05 (0.86–1.27) 0.644
  1. Model included 2305 patients and met the assumption of constant proportional hazards
  2. Non-op non-operative, post-op postoperative, SAPS Simplified Acute Physiology Score
  3. aData from five patients were missing and assumed to be normal
  4. bPatients with missing data were assumed not to have the chronic condition. Number of patients with imputed data according to comorbidity: arteriosclerosis 24, chronic kidney disease 9, chronic obstructive pulmonary disease 14, diabetes 4, hypertension 14, liver failure 24, malignancy 136, rheumatoid disease 18, systolic heart failure 21, and thrombophilia 11
  5. cData missing from 31 patients