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Table 1 Multivariate Cox proportional hazard regression analysis on treatment effects among medical patients (a) and non-medical patients (b)

From: Glutamine, fish oil and antioxidants in critical illness: MetaPlus trial post hoc safety analysis

Parameter Parameter estimate Standard error Hazard ratio 95% CI of the hazard ratio P value
1a: Medical patients (n = 109)
IMHP versus HP 0.922 0.319 2.515 [1.360, 4.783] 0.004
Age group 1 versus 4 −2.651 0.788 0.071 [0.011, 0.275] <0.001
Age group 2 versus 4 −1.439 0.393 0.237 [0.110, 0.522] <0.001
Age group 3 versus 4 −1.120 0.409 0.326 [0.145, 0.733] 0.006
APACHE-II score 0.017 0.019 1.017 [0.980, 1.057] 0.376
2a: Non-medical patients (n = 192)
IMHP versus HP −0.034 0.296 0.967 [0.540, 1.736] 0.909
Age group 1 versus 4 −1.595 0.533 0.203 [0.068, 0.562] 0.003
Age group 2 versus 4 −1.489 0.434 0.226 [0.095, 0.531] <0.001
Age group 3 versus 4 −0.467 0.381 0.627 [0.299, 1.353] 0.219
APACHE-II score 0.101 0.026 1.106 [1.052, 1.165] <0.001
  1. IMHP immune-modulating high-protein enteral nutrition, HP high-protein enteral nutrition, age group 1 age ≤50 year, age group 2 age 51–70 years, age group 3 age 71–80 years, age group 4 age >80 years, APACHE-II acute physiology and chronic health evaluation-II