Skip to main content
Annals of Intensive Care

Table 3 Unadjusted and adjusted 4-year prognostic analysis for the 1660 patients who survived the ICU stay

From: Patients with preexisting psychiatric disorders admitted to ICU: a descriptive and retrospective cohort study

Variable

Non adjusted hazard ratio

95% Confident interval

P value

Adjusted hazard ratio

95% Confident interval

P value

Age (1-year increment)

1.053

1.041–1.066

<0.0001

1.030

1.016–1.044

<0.0001

Male gender

1.01

0.69–1.46

0.96

   

SAPS II score (1-point increment)

1.037

1.035–1.049

<0.0001

1.023

1.010–1.036

<0.01

Mental disorder

 Anxiety disorder

0.47

0.21–1.07

0.07

   

 Schizophrenia

1.67

0.87–3.20

0.12

   

 Psychotic disorder other than schizophrenia

1.57

0.98–2.52

0.06

   

 Depression disorder

0.80

0.55–1.16

0.24

   

 Bipolar disorder

1.18

0.65–2.14

0.59

   

Substance dependence (alcohol or drug addiction)

1.12

0.79–1.16

0.42

   

Transfer from psychiatric hospital or ward

1.79

1.01–3.19

0.04

   

Psychoactive medication before admission

 None

1.17

0.72–2.05

0.58

   

 Benzodiazepines

0.97

0.80–1.90

0.80

   

 Neuroleptics

1.16

0.78–1.72

0.47

   

 Antipsychotics other than neuroleptics

1.08

0.80–1.47

0.60

   

 Lithium

1.59

0.77–3.26

0.21

   

 SSRIs

0.84

0.53–1.32

0.44

   

 SNRIs

0.34

0.11–1.05

0.48

   

 Tri- or tetracyclics antidepressants

0.52

0.21–1.27

0.52

   

 MAOIs

0.89

0.63–1.24

0.42

   

Reason for admission

 Deliberate self-poisoning with psychoactive medications alone

0.30

0.20–0.44

<0.0001

   

 Deliberate self-poisoning with psychoactive medications and/or non-psychoactive medications

0.11

0.10–0.78

0.03

   

 Deliberate self-poisoning with psychoactive medications and/or with pesticides, household or industrial products

0.45

0.17–1.19

0.11

   

 Deliberate self-poisoning with psychoactive medications and/or with hanging, drowning, jumping from buildings or corrosive chemicals ingestion

1.06

0.12–2.84

0.86

   

 Respiratory failure

3.28

2.11–3.99

<0.0001

2.33

1.19–4.57

0.01

 Shock

6.30

3.76–5.92

<0.0001

3.72

1.97–6.62

<0.001

 CNS or peripheral disorder

2.18

1.14–4.17

0.02

   

 Metabolic disorder

1.50

0.61–3.67

<0.38

   

 Out-of-hospital cardiac arrest

4.52

0.63–7.79

0.13

   

 Acute kidney injury

4.35

1.27–6.24

0.01

   

 Non-deliberate psychoactive medication overdose

1.34

0.56–3.71

0.54

   

 Miscellaneous

1.50

0.48–4.43

0.48

   

Chemical pneumonitis and/or aspiration pneumonia [n (%)]

1.18

0.67–1.57

0.99

   

Organ support in the ICU

 Invasive mechanical ventilation

0.84

0.57–1.24

0.38

   

 Vasopressors

2.01

1.39–3.10

<0.0001

   

 Renal replacement therapy

1.89

1.11–2.21

0.02

   

ICU outcomes

 Acquired infection at any site

2.62

1.87–5.37

<0.01

   
  1. SAPS simplified acute physiologic score, CNS central nervous system, SSRIs selective serotonin reuptake inhibitors, SNRIs selective norepinephrine reuptake inhibitors, MAOIs monoamine oxidase inhibitors
Back to article page