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Table 1 Characteristics of 90-day survivors and non-survivors

From: Adrenomedullin: a marker of impaired hemodynamics, organ dysfunction, and poor prognosis in cardiogenic shock

 

Survivors

(n = 103)

Non-survivors

(n = 75)

P value

Age

63 (13)

71 (11)

<0.001

Male gender

82 (80%)

51 (68%)

0.08

CardShock risk score

3.4 (1.7)

5.5 (1.5)

<0.001

Medical history

 Hypertension

59 (57%)

51 (68%)

0.15

 Hyperlipidemia

41 (40%)

44 (59%)

0.013

 Diabetes

23 (22%)

30 (40%)

0.011

 Smoker

48 (47%)

23 (31%)

0.032

 Ischemic heart disease

23 (22%)

36 (48%)

<0.001

 Previous infarction

16 (16%)

29 (39%)

<0.001

 Previous CABG

1 (1%)

10 (13%)

0.001

 Chronic heart failure

13 (13%)

16 (21%)

0.12

 Stroke or TIA

8 (8%)

8 (11%)

0.5

 Peripheral artery disease

6 (6%)

13 (17%)

0.014

 Asthma or COPD

11 (11%)

9 (12%)

0.8

Status at inclusion

 Altered mental status

56 (55%)

61 (81%)

<0.001

 Systolic BP, mmHg

80 (70–85)

75 (66–80)

0.016

 Mean BP, mmHg

58 (53–64)

53 (47–60)

0.011

 Heart rate

88 (27)

89 (31)

0.94

 LVEF,  %

36 (15)

29 (12)

<0.001

 hs-TnT, ng/L

1366 (183–4191)

2862 (1124–7842)

0.008

 NT-proBNP, ng/L

2026 (443–7101)

5174 (1447–16,547)

0.001

 eGFR, ml/min/1.72m2

71 (29)

51 (27)

<0.001

 Post-resuscitation

20 (19%)

27 (36%)

0.013

Etiology of cardiogenic shock

   

 Acute coronary syndrome

77 (75%)

65 (87%)

0.051

  Left main stenosis

11 (14%)

15 (25%)

0.09

  Three-vessel disease

17 (22%)

25 (42%)

0.008

  PCI

66 (88%)

52 (80%)

0.2

  Thrombolysis

12 (16%)

5 (8%)

0.13

 Myocarditis or Takotsubo

8 (8%)

0 (0%)

 

 Valvular cause

6 (6%)

6 (8%)

0.6

 Chronic cardiomyopathy/heart failure

11 (11%)

4 (5%)

0.2

In-hospital management

   

 Any inotrope

74 (76%)

54 (81%)

0.5

 Any vasopressor

75 (76%)

64 (94%)

0.002

 Invasive ventilation

54 (52%)

56 (75%)

0.003

 IABP treatment

51 (50%)

45 (60%)

0.17

 ECMO

2 (2%)

1 (1%)

0.8

 LVAD

1 (1%)

4 (6%)

0.08

  1. Continuous variables expressed as mean (standard deviation) or median (interquartile range), as appropriate; categorical variables expressed as number (percentage). BMI body mass index, CABG coronary artery bypass graft surgery, COPD chronic obstructive pulmonary disease, TIA transient ischemic attack, BP blood pressure, LVEF left ventricular ejection fraction, hs-TnT high sensitive troponin T, NT-proBNP N-terminal pro-brain natriuretic peptide, eGFR estimated glomerular filtration rate, PCI percutaneous coronary intervention, IABP intra-aortic balloon pump, LVAD left ventricular assist device, ECMO extracorporeal membrane oxygenation