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Table 2 Univariable logistic regression of early risk factors for ARDS in sepsis cohort

From: Early risk factors and the role of fluid administration in developing acute respiratory distress syndrome in septic patients

  Odds ratio (95% CI) p value
APACHE II 1.11 (1.08–1.13) <0.001
Age (years) 0.99 (0.98–1.0) 0.01
Total fluid infused during first 6 h (L) 1.40 (1.28–1.54) <0.001
Race   
 White Reference Reference
 Black 0.62 (0.41–0.94) 0.02
 Asian 1.31 (0.39–4.34) 0.59
 Other 1.34 (0.82–2.19) 0.25
Shock 4.52 (3.10–6.61) <0.001
Gender (male) 1.48 (1.06–2.06) 0.02
Pneumonia as site of infection 1.51 (1.09–2.10) 0.01
Alcohol use 1.19 (0.82–1.74) 0.36
Blood product transfusion 4.10 (2.00–8.41) <0.001
Aspiration 2.77 (1.56–4.91) <0.001
Pancreatitis 4.11 (1.51–11.16) 0.003
Acute abdomen 2.60 (1.08–6.27) 0.03
Obesity (BMI > 30) 1.29 (0.90–1.86) 0.16
Chemotherapy 1.28 (0.66–2.49) 0.47
Diabetes mellitus 0.64 (0.43–0.95) 0.03
Tobacco use   
 Never Reference Reference
 Former 0.88 (0.59–1.33) 0.56
 Current 0.99 (0.65–1.51) 0.81
Emergency surgery 2.16 (0.83–5.57) 0.11
Tachypnea (RR > 30) 2.52 (1.65–3.86) <0.001
Hypoxemia (SpO2 < 95%) 1.54 (1.11–2.14) 0.01
FIO2 >0.35 3.86 (2.72–5.46) <0.001
  1. For continuous variables, the odds ratio indicates the increased odds of ARDS for a 1-unit increase of the variable
  2. APACHE Acute Physiology and Chronic Health Evaluation, BMI body mass index, RR respiratory rate