Table 2 Univariable logistic regression of early risk factors for ARDS in sepsis cohort

APACHE II

1.11 (1.08–1.13)

<0.001

Age (years)

0.99 (0.98–1.0)

0.01

Total fluid infused during first 6 h (L)

1.40 (1.28–1.54)

<0.001

Race

 White

Reference

Reference

 Black

0.62 (0.41–0.94)

0.02

 Asian

1.31 (0.39–4.34)

0.59

 Other

1.34 (0.82–2.19)

0.25

Shock

4.52 (3.10–6.61)

<0.001

Gender (male)

1.48 (1.06–2.06)

0.02

Pneumonia as site of infection

1.51 (1.09–2.10)

0.01

Alcohol use

1.19 (0.82–1.74)

0.36

Blood product transfusion

4.10 (2.00–8.41)

<0.001

Aspiration

2.77 (1.56–4.91)

<0.001

Pancreatitis

4.11 (1.51–11.16)

0.003

Acute abdomen

2.60 (1.08–6.27)

0.03

Obesity (BMI > 30)

1.29 (0.90–1.86)

0.16

Chemotherapy

1.28 (0.66–2.49)

0.47

Diabetes mellitus

0.64 (0.43–0.95)

0.03

Tobacco use

 Never

Reference

Reference

 Former

0.88 (0.59–1.33)

0.56

 Current

0.99 (0.65–1.51)

0.81

Emergency surgery

2.16 (0.83–5.57)

0.11

Tachypnea (RR > 30)

2.52 (1.65–3.86)

<0.001

Hypoxemia (SpO₂ < 95%)

1.54 (1.11–2.14)

0.01

FIO₂ >0.35

3.86 (2.72–5.46)

<0.001