Early risk factors and the role of fluid administration in developing acute respiratory distress syndrome in septic patients

Annals of Intensive Care

Table 3 Multivariable logistic regression of early risk factors for ARDS in sepsis cohort

	Odds ratio (95% CI)	p value
APACHE II	1.10 (1.07–1.13)	<0.001
Age (years)	0.97 (0.96–0.98)	<0.001
Total fluid infused during first 6 h (L)	1.15 (1.03–1.29)	0.01
Shock	2.57 (1.62–4.08)	<0.001
Gender (male)	1.30 (0.92–1.85)	0.14
Race
White	Reference	Reference
Black	0.56 (0.36–0.87)	0.08
Asian	1.14 (0.32–4.11)	0.58
Other	1.14 (0.66–1.96)	0.29
Pneumonia as site of infection	2.31 (1.59–3.36)	<0.001
Pancreatitis	3.86 (1.33–11.24)	0.01
Acute abdomen	3.77 (1.37–10.41)	0.01
Diabetes mellitus	0.74 (0.48–1.12)	0.16
Tachypnea (RR > 30)	1.41 (1.00–1.97)	0.05

For continuous variables, the odds ratio indicates the increased odds of ARDS for a 1-unit increase in the variable
APACHE Acute Physiology and Chronic Health Evaluation, RR respiratory rate