Day of MV | Day 0 | Day 1 | Day 2 | Day 3 | ||||
---|---|---|---|---|---|---|---|---|
First | Second | First | Second | First | Second | First | Second | |
Measurements (n) | 80 | 38 | 88 | 65 | 66 | 37 | 51 | 36 |
PaO2/FiO2 (mmHg), median (IQR)* | ||||||||
Facial TOF = 0 | 115 (82–154) | 170 (100–209) | 148 (116–231) | 171 (143–192) | 178 (128–212) | 151 (105–196) | 160 (118–201) | 136 (114–183) |
Facial TOF = 1–2 | 111 (93–206) | 160 (107–220) | 203 (121–269) | 142 (121–178) | 198 (154–228) | – | 183 (146–213) | 121 (113–130) |
Facial TOF = 3–4 | 98 (77–148) | 168 (137–246) | 159 (128–198) | 195 (162–239) | 185 (140–232) | 220 (210–240) | 187 (130–211) | 154 (140–184) |
Plateau pressure, cmH2O, median (IQR)* | ||||||||
Facial TOF = 0 | 24 (19–26) | 22 (20–25) | 23 (19–25) | 22 (20–24) | 22 (20–24) | 24 (20–25) | 23 (20–25) | 23 (22–26) |
Facial TOF = 1–2 | 27 (23–27) | 23 (23–24) | 21 (17–23) | 21 (19–27) | 20 (18–20) | – | 24 (21–26) | 21 (17–25) |
Facial TOF = 3–4 | 22 (20–27) | 21 (20–22) | 22 (20–24) | 22 (21–24) | 22 (20–24) | 22 (20–24) | 22 (19–24) | 23 (20–25) |
Driving pressure, cmH2O, median (IQR)* | ||||||||
Facial TOF = 0 | 11 (9.5–18) | 11 (8.5–14) | 11 (9–13) | 10 (9–12) | 11 (9–13) | 12 (10–14) | 12 (11–17) | 13 (11–17) |
Facial TOF = 1–2 | 12 (12–14) | 11 (10–12) | 9 (9–11.5) | 10 (8–15) | 9.5 (8–11.5) | – | 11.5 (10–14) | 10 (9–11) |
Facial TOF = 3–4 | 12 (10–16) | 10.5 (8.5–12) | 11 (10–14) | 11 (9.5–13) | 11 (9–13) | 11 (8.5–12.5) | 10 (9.5–13.5) | 12 (9.5–15) |