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Table 3 MR-proADM cut-off (nmol/L) with the highest accuracy for predicting 28-day mortality based on SOFA score

From: Superior accuracy of mid-regional proadrenomedullin for mortality prediction in sepsis with varying levels of illness severity

  Cut-off Sensitivity Specificity PPV NPV +LR −LR
SOFA < 6 1.79 83.0 61.0 23.8 96.2 2.14 0.27
SOFA 7–12 3.25 83.0 52.0 43.4 87.0 1.74 0.33
SOFA ≥ 13 5.58 83.8 60.0 75.6 71.4 2.09 0.27
  1. PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio