Table 2 Patient characteristics during and 24 h after surgery
From: Goal-directed fluid restriction during brain surgery: a prospective randomized controlled trial
GDFR group (n = 73) | Control group (n = 72) | p value | |
|---|---|---|---|
Patient position | |||
Supine position (n) | 41 | 45 | 0.500 |
Left-lateral position (n) | 18 | 14 | 0.549 |
Right-lateral position (n) | 12 | 10 | 0.818 |
Prone position (n) | 2 | 3 | 0.679 |
Beginning of surgery | |||
CI (ml/min/m2) | 3 ± 1.2 | NA | NA |
SVV (%) | 12 ± 5 | NA | NA |
During surgery | |||
Crystalloids (ml/kg/h) | 3 ± 0 | 5.0 ± 2.8 | <0.001 |
Colloids (ml/kg/h) | 1.9 ± 1.1 | 3.9 ± 1.6 | 0.021 |
Colloids (ml) | 563 ± 550 | 1050 ± 548 | <0.001 |
Colloids (nb of bolus per patient) | 3 ± 3 | 5 ± 3 | <0.001 |
Autologous blood transfusion (ml) | n = 5, 280 ± 109 | n = 14, 375 ± 198 | 0.224 |
Red blood cell (ml) | n = 3, 400 ± 200 | n = 2, 400 ± 282 | 0.089 |
Fresh frozen plasma (ml) | 0 | 0 | 1 |
Estimated blood loss (ml) | 287 ± 179 | 305 ± 273 | 0.535 |
Metaraminol (no. of patients) | 39 | 18 | <0.001 |
Ephedrine (no. of patients) | 40 | 21 | <0.001 |
Dopamine (no. of patients) | 5 | 3 | 0.479 |
Dobutamine (no. of patients) | 1 | 0 | 0.319 |
Norepinephrine (no. of patients) | 3 | 3 | 0.981 |
End of surgery | |||
CI (ml/min/m2) | 3.6 ± 0.7 | NA | NA |
SVV (%) | 7 ± 2 | NA | NA |
Length of surgery (min) | 274 ± 72 | 276 ± 66 | 0.864 |
Dopamine (n) | 1 | 0 | 0.319 |
Norepinephrine (n) | 0 | 1 | 0.312 |
24 h after surgery | |||
Crystalloids (ml/kg/h) | 2.6 ± 1.3 | 2.6 ± 0.8 | 0.881 |
Colloids (ml/kg/h) | 0.2 ± 0.3 | 0.2 ± 0.3 | 0.868 |
Blood (ml/kg/h) | 0 | 0 | 0.746 |
Fresh frozen plasma (ml) | 0 | 0 | 0.744 |
Estimated blood loss (ml) | 98 ± 65 | 115 ± 99 | 0.206 |
Norepinephrine (n) | 3 | 3 | 0.981 |
Dopamine (n) | 5 | 3 | 0.479 |
Vasodilatation therapy (n) | 5 | 11 | 0.105 |
Diuretic support (n) | 45 | 38 | 0.281 |