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Table 2 Patient characteristics during and 24 h after surgery

From: Goal-directed fluid restriction during brain surgery: a prospective randomized controlled trial

  GDFR group (n = 73) Control group (n = 72) p value
Patient position
 Supine position (n) 41 45 0.500
 Left-lateral position (n) 18 14 0.549
 Right-lateral position (n) 12 10 0.818
 Prone position (n) 2 3 0.679
Beginning of surgery
 CI (ml/min/m2) 3 ± 1.2 NA NA
 SVV (%) 12 ± 5 NA NA
During surgery
 Crystalloids (ml/kg/h) 3 ± 0 5.0 ± 2.8 <0.001
 Colloids (ml/kg/h) 1.9 ± 1.1 3.9 ± 1.6 0.021
 Colloids (ml) 563 ± 550 1050 ± 548 <0.001
 Colloids (nb of bolus per patient) 3 ± 3 5 ± 3 <0.001
 Autologous blood transfusion (ml) n = 5, 280 ± 109 n = 14, 375 ± 198 0.224
 Red blood cell (ml) n = 3, 400 ± 200 n = 2, 400 ± 282 0.089
 Fresh frozen plasma (ml) 0 0 1
 Estimated blood loss (ml) 287 ± 179 305 ± 273 0.535
 Metaraminol (no. of patients) 39 18 <0.001
 Ephedrine (no. of patients) 40 21 <0.001
 Dopamine (no. of patients) 5 3 0.479
 Dobutamine (no. of patients) 1 0 0.319
 Norepinephrine (no. of patients) 3 3 0.981
End of surgery
 CI (ml/min/m2) 3.6 ± 0.7 NA NA
 SVV (%) 7 ± 2 NA NA
 Length of surgery (min) 274 ± 72 276 ± 66 0.864
 Dopamine (n) 1 0 0.319
 Norepinephrine (n) 0 1 0.312
24 h after surgery
 Crystalloids (ml/kg/h) 2.6 ± 1.3 2.6 ± 0.8 0.881
 Colloids (ml/kg/h) 0.2 ± 0.3 0.2 ± 0.3 0.868
 Blood (ml/kg/h) 0 0 0.746
 Fresh frozen plasma (ml) 0 0 0.744
 Estimated blood loss (ml) 98 ± 65 115 ± 99 0.206
 Norepinephrine (n) 3 3 0.981
 Dopamine (n) 5 3 0.479
 Vasodilatation therapy (n) 5 11 0.105
 Diuretic support (n) 45 38 0.281
  1. Values are presented as mean ± standard deviation
  2. CI cardiac index, HR heart rate, MAP mean arterial pressure, N/A not applicable, SVV stroke volume variation