Table 1 Profile of patients with severe sepsis in Catalonia 2008–2012
From: Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European setting
Total N = 82,300 | Alive on discharge N = 64,511 | Dead on discharge N = 17,789 | p | |
|---|---|---|---|---|
Mean (SD) | Mean (SD) | Mean (SD) | ||
Age (years) | 71.2 (19.7) | 70.6 (20.4) | 73.3 (16.6) | <.0001 |
Length of hospital stay (days) | 16.7 (19.5) | 16.8 (19.3) | 16.3 (20.3) | <.001 |
Charlson comorbidity index | 5.1 (2.6) | 5.0 (2.6) | 5.6 (2.7) | <.0001 |
% | % | % | p | |
|---|---|---|---|---|
Age (years) | ||||
<15 | 3.2 | 3.7 | 1.4 | <.0001 |
15–44 | 6.1 | 6.6 | 4.2 | |
45–64 | 16.4 | 16.2 | 17.3 | |
65–74 | 17.5 | 17.3 | 18.4 | |
75–84 | 32.9 | 32.8 | 33.6 | |
>84 | 23.8 | 23.5 | 25.0 | |
Sex | ||||
Males | 56.7 | 56.1 | 59.0 | <.0001 |
Comorbidities | ||||
Chronic kidney disease | 23.8 | 24.5 | 20.9 | <.0001 |
COPD | 22.4 | 22.9 | 20.6 | <.0001 |
Cancer | 14.5 | 12.5 | 21.5 | <.0001 |
Metastasis | 4.8 | 5.8 | 8.3 | <.0001 |
Peripheral vascular disease | 4.4 | 4.2 | 4.9 | <.0001 |
Complicated diabetes | 4.0 | 4.3 | 3.0 | <.0001 |
Liver disease: mild | 9.7 | 8.7 | 13.1 | <.0001 |
Liver disease: moderate–severe | 3.0 | 2.4 | 4.9 | <.0001 |
Myocardial infarction | 3.8 | 3.6 | 4.7 | <.0001 |
Congestive heart failure | 20.1 | 19.1 | 23.8 | <.0001 |
Cerebrovascular disease | 6.7 | 6.5 | 7.6 | <.0001 |
AIDS/HIV infection | 1.0 | 0.9 | 1.3 | <.0001 |
Emergency stay (%) | 89.4 | 89.8 | 87.8 | <.0001 |
ICU admissions | 28.2 | 22.3 | 49.8 | <.0001 |
Admission year | ||||
2008 | 15.6 | 15.1 | 17.1 | <.0001 |
2009 | 17.9 | 17.4 | 19.6 | |
2010 | 19.7 | 19.6 | 20.0 | |
2011 | 22.3 | 22.6 | 21.0 | |
2012 | 24.6 | 25.2 | 22.3 | |
Sepsis origins | ||||
Urinary | 37.2 | 41.1 | 23.0 | <.0001 |
Respiratory | 32.5 | 31.4 | 36.4 | <.0001 |
Abdominal | 11.0 | 10.1 | 14.3 | <.0001 |
Skin and soft tissues | 4.1 | 4.2 | 3.9 | .06 |
Endocarditis | 1.6 | 1.5 | 2.0 | <.0001 |
Device-related | 1.1 | 1.2 | 0.6 | <.0001 |
CNS | 0.9 | 0.9 | 1.2 | <.0001 |
Others | 37.9 | 41.0 | 26.5 | <.0001 |
Bacteraemia | 24.7 | 19.1 | 44.9 | <.0001 |
Organ dysfunction | ||||
Kidney | 58.4 | 56.9 | 63.7 | <.0001 |
Lung | 20.5 | 15.7 | 37.9 | <.0001 |
CNS | 19.7 | 21.6 | 12.7 | <.0001 |
Haematologic | 11.1 | 11.0 | 11.5 | .054 |
Cardiovascular | 4.9 | 5.2 | 3.6 | <.0001 |
Liver | 1.3 | 0.7 | 3.3 | <.0001 |
Number of organ failures | ||||
1 | 86.3 | 89.7 | 72.9 | <.0001 |
2 | 12.0 | 9.4 | 21.8 | |
3 | 1.6 | 0.8 | 4.7 | |
4 or more | 0.2 | 0.1 | 0.6 | |