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Table 1 Profile of patients with severe sepsis in Catalonia 2008–2012

From: Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European setting

  Total N = 82,300 Alive on discharge N = 64,511 Dead on discharge N = 17,789 p
Mean (SD) Mean (SD) Mean (SD)
Age (years) 71.2 (19.7) 70.6 (20.4) 73.3 (16.6) <.0001
Length of hospital stay (days) 16.7 (19.5) 16.8 (19.3) 16.3 (20.3) <.001
Charlson comorbidity index 5.1 (2.6) 5.0 (2.6) 5.6 (2.7) <.0001
  1. Data are presented as mean and standard deviation or %
  2. AIDS acquired immune deficiency syndrome, CNS central nervous system, COPD chronic obstructive pulmonary disease, HIV human immunodeficiency virus, ICU intensive care unit
  % % % p
Age (years)
 <15 3.2 3.7 1.4 <.0001
 15–44 6.1 6.6 4.2  
 45–64 16.4 16.2 17.3  
 65–74 17.5 17.3 18.4  
 75–84 32.9 32.8 33.6  
 >84 23.8 23.5 25.0  
Sex
 Males 56.7 56.1 59.0 <.0001
Comorbidities
 Chronic kidney disease 23.8 24.5 20.9 <.0001
 COPD 22.4 22.9 20.6 <.0001
 Cancer 14.5 12.5 21.5 <.0001
 Metastasis 4.8 5.8 8.3 <.0001
 Peripheral vascular disease 4.4 4.2 4.9 <.0001
 Complicated diabetes 4.0 4.3 3.0 <.0001
 Liver disease: mild 9.7 8.7 13.1 <.0001
 Liver disease: moderate–severe 3.0 2.4 4.9 <.0001
 Myocardial infarction 3.8 3.6 4.7 <.0001
 Congestive heart failure 20.1 19.1 23.8 <.0001
 Cerebrovascular disease 6.7 6.5 7.6 <.0001
 AIDS/HIV infection 1.0 0.9 1.3 <.0001
Emergency stay (%) 89.4 89.8 87.8 <.0001
ICU admissions 28.2 22.3 49.8 <.0001
Admission year
 2008 15.6 15.1 17.1 <.0001
 2009 17.9 17.4 19.6  
 2010 19.7 19.6 20.0  
 2011 22.3 22.6 21.0  
 2012 24.6 25.2 22.3  
Sepsis origins
 Urinary 37.2 41.1 23.0 <.0001
 Respiratory 32.5 31.4 36.4 <.0001
 Abdominal 11.0 10.1 14.3 <.0001
 Skin and soft tissues 4.1 4.2 3.9 .06
 Endocarditis 1.6 1.5 2.0 <.0001
 Device-related 1.1 1.2 0.6 <.0001
 CNS 0.9 0.9 1.2 <.0001
 Others 37.9 41.0 26.5 <.0001
Bacteraemia 24.7 19.1 44.9 <.0001
Organ dysfunction
 Kidney 58.4 56.9 63.7 <.0001
 Lung 20.5 15.7 37.9 <.0001
 CNS 19.7 21.6 12.7 <.0001
 Haematologic 11.1 11.0 11.5 .054
 Cardiovascular 4.9 5.2 3.6 <.0001
 Liver 1.3 0.7 3.3 <.0001
Number of organ failures
 1 86.3 89.7 72.9 <.0001
 2 12.0 9.4 21.8  
 3 1.6 0.8 4.7  
 4 or more 0.2 0.1 0.6  
  1. Data are presented as mean and standard deviation or %
  2. AIDS acquired immune deficiency syndrome, CNS central nervous system, COPD chronic obstructive pulmonary disease, HIV human immunodeficiency virus, ICU intensive care unit