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Table 2 Overall mortality by patient characteristics, sepsis origins, presence of bacteraemia and organ dysfunction by year of admission in Catalonia (2008–2012)

From: Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European setting

Condition N Presence of condition (%) In-hospital mortality (%)
2008 2009 2010 2011 2012 p
Mortality   23.7 23.6 22.0 20.4 19.7 <.0001  
Source of sepsis
 Urinary tract 30,600 33.6 35.0 37.1 39.8 38.8 <.0001 13.9
 Respiratory tract 26,748 34.2 34.0 31.2 30.9 32.7 <.0001 24.2
 Abdomen 9065 10.7 11.2 11.3 11.0 10.9 NS 28.0
 Skin and soft tissues 3394 3.9 4.0 4.0 4.4 4.2 NS 20.3
 Endocarditis 1326 1.8 1.8 1.9 1.4 1.4 <.0001 27.3
 Device-related 869 1.1 1.1 1.2 1.1 0.9 .016 11.6
 CNS 775 1.2 1.1 1.1 0.7 0.7 <.0001 27.5
 Other 31,149 37.4 37.5 39.2 38.1 37.1 .001 15.1
Bacteraemia 20,285 25.5 25.5 24.5 24.8 23.5 <.0001 39.3
Organ dysfunction
 Kidney 48,072 50.8 53.5 57.1 61.9 64.7 <.0001 23.6
 Respiratory 16,876 26.1 24.1 20.9 17.9 16.3 <.0001 40.0
 CNS 16,177 20.5 19.6 19.1 18.9 20.3 <.0001 13.9
 Haematologic 9158 11.6 12.3 12.2 11.2 9.1 <.0001 22.4
  Cardiovascular 3988 5.3 5.4 4.7 4.6 4.4 <.0001 16.1
  Liver 1058 1.0 1.3 1.3 1.3 1.4 .029 55.9
Number of organ failures
 1 70,874 86.6 85.9 86.5 86.0 85.8 NS 18.5
 2 9964 11.7 12.2 11.8 12.4 12.3   39.0
 3 or more 1462 1.7 1.9 1.9 1.7 1.8   63.4
  1. Data are presented as number of cases or %
  2. CNS central nervous system, NS non-significant