Table 1 Baseline patient demographics and clinical characteristics for the overall study population and by survivor status
From: Outcomes in elderly patients admitted to the intensive care unit with solid tumors
Overall (n = 262) | ICU survivors (n = 174) | ICU non-survivors (n = 88) | p value | |
|---|---|---|---|---|
Age (years) | 75.2 ± 6.7 | 75.7 ± 6.8 | 74.3 ± 6.5 | 0.13 |
Male | 162 (61.8) | 101 (58.0) | 61 (69.3) | 0.08 |
Comorbidities | ||||
Tobacco use | 106 (40.5) | 65 (37.4) | 41 (46.6) | 0.15 |
Diabetes | 57 (21.8) | 35 (20.1) | 22 (25) | 0.36 |
Chronic respiratory failure | 33 (12.6) | 23 (13.2) | 10 (11.4) | 0.18 |
Chronic kidney failure | 29 (11.1) | 23 (13.2) | 6 (6.8) | 0.12 |
Primary tumor site | 0.02 | |||
Gastrointestinal | 71 (27.1) | 52 (29.9) | 19 (21.6) | |
Lung | 68 (26) | 45 (25.9) | 23 (26.1) | |
Genitourinary | 60 (22.9) | 43 (24.7) | 17 (19.3) | |
Head and neck | 31 (11.8) | 11 (6.3) | 20 (22.7) | |
Breast | 18 (6.9) | 13 (7.5) | 5 (5.7) | |
Gynecological | 9 (3.4) | 7 (4) | 2 (2.3) | |
Sarcoma | 3 (1.1) | 2 (1.2) | 1 (1.1) | |
Unknown | 2 (0.8) | 1 (0.6) | 1 (1.1) | |
Metastasis | ||||
Yes | 158 (60.3) | 110 (63.2) | 48 (54.6) | 0.17 |
Other | 66 (25.3) | 42 (24.3) | 24 (27.3) | 0.58 |
Lymph node | 58 (22.2) | 39 (22.5) | 19 (21.6) | 0.93 |
Lung | 57 (21.8) | 41 (23.7) | 16 (18.2) | 0.32 |
Bone | 46 (17.6) | 31 (17.9) | 15 (17.1) | 0.88 |
Liver | 38 (14.6) | 26 (15) | 12 (13.6) | 0.78 |
Brain | 9 (3.5) | 6 (3.5) | 3 (3.4) | 0.73 |
Pulmonary lymphangitis | 6 (2.3) | 4 (2.3) | 2 (2.3) | 0.67 |
Missing | 1 (0.4) | 1 (0.6) | 0 (0) | |
Anticancer treatment before ICU admission | ||||
Number of previous systemic anti-tumoral treatments [median (IQR)] | 1 (0;1) | 1 (0;1) | 1 (0;1) | 0.32 |
Missing | 8 (3) | 5 (2.9) | 3 (3.4) | |
Chemotherapy | 94 (56.3) | 66 (60.6) | 28 (48.3) | 0.18 |
Targeted therapy | 31 (18.7) | 22 (20.2) | 9 (15.8) | |
Missing | 95 (36.3) | 65 (37.3) | 30 (34) | |
Performance status | ||||
0 or 1 | 98 (46.4) | 64 (45.7) | 34 (47.9) | 0.98 |
2 | 86 (40.8) | 58 (41.4) | 28 (39.4) | |
3 or 4 | 27 (12.9) | 18 (12.8) | 9 (12.7) | |
Missing | 51 (19.5) | 34 (19.5) | 17 (19.3) | |