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Table 2 Baseline patient ICU details for the overall study population and by survivor status

From: Outcomes in elderly patients admitted to the intensive care unit with solid tumors

 

Overall (n = 262)

ICU survivors (n = 174)

ICU non-survivors (n = 88)

p value

Reason for ICU admission [n (%)]

0.42

 Not related to cancer

174 (66.4)

120 (68.9)

54 (61.4)

 

 Related to anticancer drugs

49 (18.7)

29 (16.7)

20 (22.7)

 

 Related to cancer progression

39 (14.9)

25 (14.4)

14 (15.9)

 

Reasons for ICU admission [n (%)]

<0.001

 Sepsis

80 (30.5)

57 (32.8)

3 (26.1)

 

 Acute respiratory failure

74 (28.2)

47 (27)

27 (30.8)

 

 Coma or seizure

21 (8)

12 (6.9)

9 (10.2)

 

 Cardiorespiratory shock

18 (6.9)

1 (0.5)

17 (19.3)

 

 Hemorrhagic shock

16 (6.1)

14 (8.1)

2 (2.3)

 

 Acute kidney failure

14 (5.3)

10 (5.8)

4 (4.6)

 

 Acute heart failure

10 (3.8)

8 (4.6)

2 (2.3)

 

 Chronic bronchitis exacerbation

8 (3.1)

7 (4)

1 (1.1)

 

 Electrolytic disorders

6 (2.3)

5 (2.9)

1 (1.1)

 

 Hypovolemia

5 (1.9)

4 (2.3)

1 (1.1)

 

 Intentional overdose

1 (0.4)

1 (0.5)

0 (0)

 

 Post-surgery complications

1 (0.4)

1 (0.5)

0 (0)

 

SAPS 2 score

61.9 ± 22.5

51.4 ± 13.0

82.0 ± 22.9

<0.001

 Neutropenia

19 (7.3)

12 (6.9)

7 (8)

0.75

ICU stay and treatments

 Time in ICU [days, median (IQR)]

4 (2;7)

4 (2;7)0

4 (1;8)

0.26

 Time in hospital [days, median (IQR)]

14 (5;25)

16 (8;27)

6 (2;16)

<0.001

 Mechanical ventilation

135 (51.5)

54 (31)

81 (92.1)

<0.0001

 Mechanical ventilation duration (days)

3.5 ± 6.3

2.2 ± 4.4

6.2 ± 8.3

<0.001

 Noninvasive ventilation

25 (10.3)

20 (12.9)

5 (5.7)

0.08

 Missing

19 (7.3)

19 (10.9)

0 (0)

 

 Inotropes

126 (48.3)

52 (30.1)

74 (84.1)

<0.0001

 Missing

1 (0.4)

1 (0.6)

0 (0)

 

 Inotropes duration (days)

1.4 ± 2.4

0.8 ± 1.6

2.7 ± 3.1

<0.001

 Dialysis

33 (12.6)

17 (9.8)

16 (18.2)

0.05

 Missing

1 (0.4)

1 (0.6)

0 (0)

 

 Limitation of active therapies [n (%)]

46 (17.6)

11 (6.3)

35 (39.8)

<0.001

  1. Data are mean ± SD or number of patients (%), expect for time in ICU and in hospital (median and interquartile [IQR]). Time in ICU and in hospital is median (IQR)