Table 1 Characteristics of the study population
Variable | All patients (N = 157) |
|---|---|
Sepsis criteria | 157 (100.0) |
Sepsis, N (%) | 112 (71.3) |
Septic shock, N (%) | 45 (28.7) |
Patients enrollment | |
Intensive care unit, N (%) | 94 (59.9) |
Emergency room, N (%) | 63 (40.1) |
Age (years), median [IQR] | 70 [57.7–77.0] |
Males, N (%) | 95 (60.5) |
Hospital stay (days), median [IQR] | 16 [8–40] |
In-hospital mortality, N (%) | 40 (25.5) |
30-day mortality, N (%) | 34 (21.7) |
Comorbidities | |
Hemato-oncologic, N (%) | 31 (19.6) |
Pulmonary, N (%) | 29 (18.6) |
Cerebrovascular, N (%) | 28 (17.5) |
Renal and genitourinary, N (%) | 19 (12.4) |
Gastrointestinal, N (%) | 18 (11.3) |
Cardiovascular, N (%) | 16 (10.3) |
Others, N (%) | 16 (10.3) |
Type of infections/proportion of infection episodes with isolated pathogens* | |
Bacteremia, N (%)/% | 90 (57.3)/100% |
Respiratory infection, N (%)/% | 102 (65.0)/88.2% |
Urinary infection, N (%)/% | 55 (35.0)/100% |
Gastrointestinal infection, N (%)/% | 26 (16.6)/46.2% |
Others, N (%)/% | 4 (2.5)/100% |
eGFR by MDRD Study equation (mL/min/1.73 m2), median [IQR] | 44.45 [20.83–81.33] |
SOFA score range | 2–11 |
2 (45, 28.7%); 3 (32, 20.4%); 4 (26, 16.6%); 5 (14, 8.9%); 6 (13, 8.3%); 7 (12, 7.6%); 8 (6, 3.8%); 9 (3, 1.9%); 10 (3, 1.9%); 11 (3, 1.9%) | |
CRP (mg/dL), median [IQR] | 12.54 [7.22–22.0] |
WBC (× 109/L), median [IQR] | 12.47 [8.18–17.10] |
PCT (ng/mL), median [IQR] | 6.19 [2.25–21.99] |
Presepsin (pg/mL), median [IQR] | 2714.0 [1479.3–4129.7] |
Galectin-3 (ng/mL), median [IQR] | 30.8 [17.9–58.5] |
sST2 (ng/mL), median [IQR] | 214.5 [133.6–238.8] |