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Table 2 Comparison of PCT, presepsin, galectin-3, sST2, and SOFA score according to the 30-day mortality

From: Multi-marker approach using procalcitonin, presepsin, galectin-3, and soluble suppression of tumorigenicity 2 for the prediction of mortality in sepsis

 

Total (N = 157)

30-day mortality

Survivor (N = 123)

Non-survivor (N = 34)

P*

HR (95% CI)a

P

Procalcitonin (ng/mL)

6.19 (2.24–22.39)

6.61 (2.22–20.78)

NS

Presepsin (pg/mL)

2,310.0 (1375.8–3920.2)

3,549.0 (2493.7–8242.7)

0.0011

1.33 (0.55–3.19)

NS

Galectin-3 (ng/mL)

24.5 (16.7–47.5)

58.6 (37.0–82.2)

<0.0001

7.87 (2.29–26.96)

0.0011

sST2 (ng/mL)

209.5 (116.9–236.9)

237.3 (208.8–253.3)

0.0020

1.55 (0.71–3.38)

NS

SOFA score

3 (2–5)

5 (3–8)

0.0007

2.18 (1.01–4.75)

0.0496

  1. Data are expressed as median (interquartile range)
  2. * Mann–Whitney U test
  3. aCox proportional hazard regression using dichotomized variables according to the respective optimal cutoff values for 30-day all-cause mortality derived from receiver operating characteristics curve analysis. HR was not analyzed for procalcitonin that showed no difference between survivors and non-survivors
  4. See Table 1; HR hazard ratio, NS not significant