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Table 2 Comparison of PCT, presepsin, galectin-3, sST2, and SOFA score according to the 30-day mortality

From: Multi-marker approach using procalcitonin, presepsin, galectin-3, and soluble suppression of tumorigenicity 2 for the prediction of mortality in sepsis

  Total (N = 157) 30-day mortality
Survivor (N = 123) Non-survivor (N = 34) P* HR (95% CI)a P
Procalcitonin (ng/mL) 6.19 (2.24–22.39) 6.61 (2.22–20.78) NS
Presepsin (pg/mL) 2,310.0 (1375.8–3920.2) 3,549.0 (2493.7–8242.7) 0.0011 1.33 (0.55–3.19) NS
Galectin-3 (ng/mL) 24.5 (16.7–47.5) 58.6 (37.0–82.2) <0.0001 7.87 (2.29–26.96) 0.0011
sST2 (ng/mL) 209.5 (116.9–236.9) 237.3 (208.8–253.3) 0.0020 1.55 (0.71–3.38) NS
SOFA score 3 (2–5) 5 (3–8) 0.0007 2.18 (1.01–4.75) 0.0496
  1. Data are expressed as median (interquartile range)
  2. * Mann–Whitney U test
  3. aCox proportional hazard regression using dichotomized variables according to the respective optimal cutoff values for 30-day all-cause mortality derived from receiver operating characteristics curve analysis. HR was not analyzed for procalcitonin that showed no difference between survivors and non-survivors
  4. See Table 1; HR hazard ratio, NS not significant