Acute kidney injury in the ICU: from injury to recovery: reports from the 5th Paris International Conference

Annals of Intensive Care

Table 9 AKI survivors and their long-term incidences and relative risks of mortality, CKD and ESRD

Authors [reference]	AKI severity	Study (n)	Follow-up^a (years)	Mortality		CKD		ESRD
Authors [reference]	AKI severity	Study (n)	Follow-up^a (years)	%	Relative risk^b (95% CI)	%	Relative risk^b (95% CI)	%	Relative risk^b (95% CI)
Ishani et al. [6]	AKI only AKI + CKD	233,803	2.0^c	54.3 64.3	2.48 (2.38–2.58) 3.24 (3.08–3.40)	NR	NR	2.5	13.0 (10.6–16.0) 41.2 (34.6–49.1)
Wu et al. [7]	AKI only Mild AKI Moderate AKI Severe AKI AKI + CKD	9425	4.8^c	33.3 27.4 39.1 45.0 47.2	1.62 (1.45–1.81) 2.41 (2.11–2.75) 3.06 (2.66–3.53) 3.58 (2.91–4.41)	NR	NR	1.9 0.6 0.7 5.1 30.3	2.09 (0.97–4.52) 3.19 (1.27–8.03) 22.35 (11.9–42.1) 122.9 (66.8–253.9)
Pannu et al. [3]	AKI ± CKD AKI recovery AKI non-recovery	190,714	2.8^d	30.8	1.0 1.26 (1.10, 1.43)	9.8	1.0 4.13 (3.38, 5.04)	2.1	NR
Gammelager et al. [8]	D-AKI ± CKD D-AKI only D-AKI + CKD	107,937	3.1^e	NR	NR	NR	NR	3.8	6.2 (4.7–8.1)^c 11.9 (8.5–16.8) 2.8 (1.8–4.3)
Gallagher et al. [2]	D-AKI ± CKD	810	3.6^d	31.9	NR	NR	NR	5.4	NR
Rimes-Stigare et al. [4]	AKI only	97,782	3.2^d	21.8	1.15 (1.09–1.21)	6.5	7.6 (5.5–10.4)	2.2	22.5 (12.9–39.1)

AKI acute kidney injury, CKD chronic kidney disease, ESRD end-stage renal disease, D-AKI AKI requiring dialysis in ICU, NR not reported
^aMean or median follow-up
^bAdjusted mortality rate ratio, incidence rate ratio, hazard ratio or odds ratio relative non-AKI patients or AKI recovery
^cConsidering survivors to hospital discharge
^dConsidering 90-day survivors
^eConsidering 180-day survivors