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Table 3 Characteristics of vasopressor therapy according to survival

From: Outcome of patients with septic shock and high-dose vasopressor therapy

Characteristics of vasopressor therapy All patients (n = 106) Survivors at day 28 (n = 42) Non-survivors at day 28 (n = 64) p
Maximum dose (mg/h) (mean ± SD) 14.70 ± 11.3 10.55 ± 7.74 17.46 ± 12.51 0.002
Weight-based maximum dose (µg/kg/min) (mean ± SD) 3.28 ± 2.41 2.26 ± 1.55 3.97 ± 2.65 <0.001
Cumulative dose (mg) (mean ± SD) 291.33 ± 342.84 332 ± 438 263 ± 261 0.32
Weight-based cumulative dose (µg/kg) (mean ± SD) 3828 ± 4300 4222 ± 5389 3565 ± 3410 0.45
Mean dose (mg/h) (mean ± SD) 5.34 ± 4.73 3.32 ± 2.93 6.68 ± 5.22 <0.001
Weight-based mean dose (µg/kg/min) (mean ± SD) 1.20 ± 1.05 0.72 ± 0.61 1.52 ± 1.16 <0.001
First 24-h mean dose (mg/h) (mean ± SD) 7.01 ± 6.89 5.05 ± 3.90 8.30 ± 8.06 0.02
First 24-h weight-base mean dose (µg/kg/min) (mean ± SD) 1.57 ± 1.52 1.12 ± 0.87 1.86 ± 1.77 0.01
Peak 6-h mean dose (mg/h) (mean ± SD) 9.96 ± 6.89 7.70 ± 6.56 11.44 ± 6.75 0.006
Peak 6-h weight-based mean dose (mean ± SD) 2.26 ± 1.57 1.69 ± 1.33 2.64 ± 1.61 0.002
Duration of treatment (h) (mean ± SD) 84.66 ± 106.13 81.79 ± 48.30 86.57 ± 131.69 0.82