Circulating bile acids predict outcome in critically ill patients

Annals of Intensive Care

Table 3 Cox hazard regression analysis of baseline TBA and bilirubin associated with 28-day mortality

Parameter	HR (95% CI)	p value
TBA	1.033 (1.018–1.049)	<0.001
TBA (age)^a	1.033 (1.017–1.049)	<0.001
TBA (age, sex)^a	1.033 (1.017–1.049)	<0.001
TBA (age, sex, bilirubin)^a	1.044 (1.014–1.075)	<0.005
TBA (age, sex, bilirubin, APACHE2)^a	1.041 (1.013–1.071)	<0.005

CI confidence interval
^aCorrected for covariates in brackets, HR, hazard ratio per increase of TBA 1 μmol/l or bilirubin 1 mg/dl