Table 2 Quality assessment of RCTs
Study | Random sequence generation | Allocation concealment | Blinding of patients | Blinding of outcome assessment | Incomplete outcome data | Selective outcome reporting | |
|---|---|---|---|---|---|---|---|
He/O2 group | Air/O2 group | ||||||
Jolliet_2003 | UNCLEAR Stated only that patients were randomized | UNCLEAR | LOW Patients blind to the type of driving gas | UNCLEAR Hard outcomes such as mortality and pre-defined criteria of intubation | LOW All results are based on all patients (ITT) | LOW All results are based on all patients (ITT) | LOW No apparent selective reporting |
Maggiore_2010 | LOW Computer-generated randomization | LOW Randomization undertaken at central site with a computer-generated allocation sequence | LOW Patients blind to the type of driving gas | UNCLEAR Hard outcomes such as mortality and pre-defined criteria of intubation | LOW All results are based on all patients (ITT) | LOW All results are based on all patients (ITT) | LOW No apparent selective reporting |
Jolliet_2016 | UNCLEAR Stated only that eligible patients were randomized | UNCLEAR | LOW Patients blind to the type of driving gas | UNCLEAR Hard outcomes such as mortality and pre-defined criteria of intubation | LOW All results are based on all patients (ITT) | LOW All results are based on all patients (ITT) | LOW No apparent selective reporting |