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Table 2 List of included studies

From: Systematic review and meta-analysis of complications and mortality of veno-venous extracorporeal membrane oxygenation for refractory acute respiratory distress syndrome

Study

Year

Centre

Type

Patients

Population

P/F ratio

MV (days)

Prone (%)

LIS

Age (years)

Heparin coating

Membrane type

Pump type

Coagulation ratiob

Max cannula size (French)

Cannulation

ECMO duration (days)

Mols et al. [59]

2000

University of Freiburg, Freiburg, Germany

CP

62

Mixed

64

10

81

3.2

35

Y

n/a

R

1.26

25

F-J

14.5

Davies et al. [36]

2009

Multicentre, Australia

CR

68

H1N1

56

2

18

3.2

34a

Y

HF-PMP

C

n/a

n/a

Mixed

10a

Mueller et al. [60]

2009

University Medical Center, Regensburg, Germany

CR

60

Mixed

64

1

n/a

3.6

53a

Y

HF-PMP

C

1.50

23

F-J

9a

Peek et al. [8]

2010

The Glenfield Hospital, Leicester, UK

RCT

68

Mixed

70a

1.5a

47

3.5a

40

n/a

HF-PP

R

1.58

n/a

n/a

9a

Noah et al. [61]

2011

Multicentre, UK

CC

69

H1N1

55a

4a

39

3.5a

36

n/a

n/a

n/a

n/a

23

n/a

9a

Patroniti et al. [62]

2011

Multicentre, Italy

CP

60

ARDS

63a

2

27

3.6

41

Y

HF-PMP

C

1.6

n/a

Mixed

9a

Schmidt et al. [27]

2013

Multicentre, France

CR

140

Mixed

53

5

61

n/a

44a

Y

HF mixed

C

1.357

n/a

Mixed

15a

Roch et al. [63]

2014

Marseille North Hospital, France

CP

85

Mixed

60

2

20

3.5

47

Y

HF mixed

C

1.28

25

F-J

9

Haneya et al. [64]

2015

University Medical Center, Regensburg, Germany

CR

262

Mixed

64

1

n/a

3.3

49

Y

HF mixed

C

1.57

31

Mixed

9

Schmidt et al. [24] (Melbourne)

2015

Alfred Hospital, Australia

CR

52

Mixed

75

1

2

n/a

37

n/a

n/a

n/a

n/a

n/a

Mixed

10

Schmidt et al. [24] (Paris)

2015

Pitié-Salpètrière Hospital, France

CR

57

Mixed

61

4

20

n/a

46

n/a

n/a

n/a

n/a

n/a

Mixed

10

Schmidt et al. [24] (Sydney)

2015

Royal Prince Alfred Hospital, Australia

CR

59

Mixed

66

2

54

n/a

40

n/a

n/a

n/a

n/a

n/a

Mixed

9

  1. CP cohort prospective, CR cohort retrospective, CC case–control, RCT randomized controlled trial, P/F ratio: PO2/FiO2 ratio, MV mechanical ventilation before ECMO initiation, LIS Lung Injury Score, HF hollow fibre, PP polypropylene, PMP polymethylpentene, C centrifugal, R rotatory, F-J femoro-jugular. Mean values are presented unless indicated
  2. aMedian values
  3. bNormalized coagulation ratio, see “Methods” section for explanation